
Ketamine
Fundamentals, Applications, Pharmacology, and Clinical Aspects
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Product details:
- Publisher Academic Press
- Date of Publication 1 November 2025
- ISBN 9780443299308
- Binding Paperback
- No. of pages500 pages
- Size 234x190 mm
- Weight 450 g
- Language English 700
Categories
Long description:
Pharmacology of Ketamine: Fundamentals, Applications, Delivery Systems and Clinical Aspects explores the multifaceted properties of ketamine for diverse applications, delving into dosing strategies, routes of administration, and their pharmacological implications. The book begins with an introduction that underscores the need to bridge research and practice. It then delves into the pharmacological intricacies of ketamine, dissecting mechanisms and dosing strategies and exploring the diverse routes of administration and their impact on ketamine's metabolites.
The book then explores the PK and PD characteristics of ketamine, followed by a deep dive into clinical applications emphasizing anesthesia, psychiatric therapy, and emerging treatments. The final part of the book covers addiction, toxicity, and future research perspectives. It will serve as a comprehensive reference tailored to the needs of both researchers and clinicians involved in the administration and study of ketamine.
Table of Contents:
1. Ketamine and its metabolites - mechanism of action
2. Ketamine pharmacokinetics and pharmacodynamics
3. Ketamine effects on brain dynamics
4. Ketamine for depression and other psychiatric diseases
5. Undestanding ketamine subjective effects
6. Ketamine for acute and chronic pain
7. Ketamine for neuropathic pain: animal and human studies
8. Ketamine for addiction treatment
9. Cardiorespiratory effects of ketamine
10. Ketamine toxicity: translating preclinical findings to adverse effects in humans
11. Recreational use of ketamine
12. Ketamine in the era of the opioid crisis
13. Future Perspectives