Neuropeptide Y and Drug Development
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Product details:
- Publisher Elsevier Science
- Date of Publication 15 November 1996
- ISBN 9780123049902
- Binding Hardback
- No. of pages209 pages
- Size 228x152 mm
- Weight 480 g
- Language English 0
Categories
Long description:
Neuropeptide Y (NPY) is a ubiquitous and important messenger in the nervous system, with a wide range of physiological roles. It is involved in the body energy balance and is one of the most potent stimuli of food intake known. NPY also acts to regulate central and peripheral autonomic functions.
This book, written by academic and industrial experts in the field, links the most recent basic experimental knowledge about NPY and its receptors with areas of clinical importance.
This book will be of interest to those working in all areas of research affected by NPY, such as food intake and energy homeostasis, cardiovascular regulation and G-protein-coupled receptors, as well as those interested in the development of drugs as NPY targets.
MoreTable of Contents:
Multiple Receptors and Multiple Actions
Central Effects of Neuropeptide Y and Its Role in Obesity and Diabetes
Neuropeptide Y in Sympathetic Nerves-Evidence for Y1 Receptor-Mediated Vascular Control
Neuropeptide Y Receptor Types in Mammalian Brain
Species Differences and Status in the Human Central Nervous System
Extraordinary Structural Diversity of Neuropeptide Y Family Receptors
The Importance of Various Parts of the Neuropeptide Y Molecule for Receptor Recognition
Peptide Antagonists of Neuropeptide Y: Design, Structure, And Pharmacological Characterization
SR 120819A or the First Generation of Orally-Active Neuropeptide Y1 Receptor Antagonists
BIBP3226, A Potent and Selective Y1 Receptor Antagonist
First Structure-Activity Studies and Localization of the Human Y1 Receptor Binding Site
Discovery of Neuropeptide Y Receptor Antagonists
