Neurofibromatosis by Romaine, Walter;

Diagnosis, Management & Clinical Outcomes

Series: Neurology - Laboratory and Clinical Research Developments;

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Product details:

Edition number 1
Publisher Nova Science Publishers, Inc (US)
Date of Publication 1 December 2014

ISBN 9781634632294
Binding Paperback
No. of pages71 pages
Size 230x155 mm
Weight 608 g
Language English

Long description:

Neurofibromatosis Type 1 (NF1) is a hereditary neurocutaneous tumour disorder that owes many of its most common features to abnormalities in neural crest-derived cells. NF1 may cause dysplasia in various tissues, even in some tissues that are non-neural crest-derived (eg: bone). While common manifestations of NF1 include café-au-lait spots and neurofibromas, vasculopathies are less common yet noteworthy complications of NF1. NF1 vasculopathies can involve vessels supplying various organs. Cerebrovascular abnormalities associated with NF1 have been sporadically described in the literature; these conditions are of interest due to the incomplete understanding of their pathogenesis and genetics. This book discusses the diagnosis, managements and clinical outcomes for neurofibromatosis.