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  • Mutation-Driven Evolution

    Mutation-Driven Evolution by Nei, Masatoshi;

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    Product details:

    • Publisher OUP Oxford
    • Date of Publication 16 October 2014

    • ISBN 9780198724100
    • Binding Paperback
    • No. of pages262 pages
    • Size 245x193x13 mm
    • Weight 500 g
    • Language English
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    Short description:

    The purpose of this book is to present a new theory of mutation-driven evolution, which is based on recent advances in genomics and evolutionary developmental biology. This theory asserts that the driving force of evolution is mutation and natural selection is of secondary importance.

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    Long description:

    The purpose of this book is to present a new mechanistic theory of mutation-driven evolution based on recent advances in genomics and evolutionary developmental biology. The theory asserts, perhaps somewhat controversially, that the driving force behind evolution is mutation, with natural selection being of only secondary importance. The word 'mutation' is used to describe any kind of change in DNA such as nucleotide substitution, gene duplication/deletion, chromosomal change, and genome duplication. A brief history of the principal evolutionary theories (Darwinism, mutationism, neo-Darwinism, and neo-mutationism) that preceded the theory of mutation-driven evolution is also presented in the context of the last 150 years of research. However, the core of the book is concerned with recent studies of genomics and the molecular basis of phenotypic evolution, and their relevance to mutation-driven evolution. In contrast to neo-Darwinism, mutation-driven evolution is capable of explaining real examples of evolution such as the evolution of olfactory receptors, sex-determination in animals, and the general scheme of hybrid sterility. In this sense the theory proposed is more realistic than its predecessors, and gives a more logical explanation of various evolutionary events.

    Mutation-Driven Evolution is suitable for graduate level students as well as professional researchers (both empiricists and theoreticians) in the fields of molecular evolution and population genetics. It assumes that the readers are acquainted with basic knowledge of genetics and molecular biology.

    [T]hose of us involved in evolution education and interested in conceptual issues relevant to evolution have a lot to learn from this book.

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    Table of Contents:

    Selectionism and Mutationism
    Neo-Darwinism and Pan-Selectionism
    Evolutionary Theories in the Neo-Darwinian Era
    Molecular Evolution
    Gene Duplication, Multigene Families, and Repetitive DNA Sequences
    Evolution of Phenotypic Characters
    Mutation and Selection in Speciation
    Adaptation and Evolution
    Mutation and Selection in Evolution
    Summary and Conclusion

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