Intracranial Stereotactic Radiosurgery by Sheehan, Jason P.; Trifiletti, Daniel M.; Niranjan, Ajay;

Short description:

This fourth edition of Intracranial Stereotactic Radiosurgery builds upon the success of its previous editions to provide a comprehensive assessment of contemporary approaches and indications for intracranial stereotactic radiosurgery (SRS).

Long description:

This fourth edition of Intracranial Stereotactic Radiosurgery builds upon the success of its previous editions to provide a comprehensive assessment of contemporary approaches and indications for intracranial stereotactic radiosurgery (SRS).
    Key topics include benign and malignant tumors, cerebrovascular abnormalities, and functional disorders. In addition, two new chapters are introduced, focusing on the application of AI to SRS for intracranial lesions and the consideration of large-scale brain networks. Authored by leading experts from across the world, this book offers a fundamental insight into the field of radiosurgery.
    Suitable for postgraduate students studying radiation therapy and medical physics, this text is a fundamental resource for all professionals and practitioners working in the fields of radiosurgery and radiation therapy.

Jason P. Sheehan is the Vice Chair and Harrison Distinguished Professor of Neurological Surgery at the University of Virginia (UVA). In addition, he is also a Professor of Radiation Oncology and Biomedical Engineering at the University of Virginia. He serves as the Editor-in-Chief of the Journal of Neuro-Oncology and Associate Editor of Neurosurgical Focus. He has held many leadership positions including ones in the American Association of Neurological Surgeons, the AANS/CNS Tumor Section, International Stereotactic Radiosurgery Society, and the International Radiosurgery Research Foundation. He has published more than 800 peer-reviewed papers in journals and contributed to and/or edited dozens of books.

Daniel M. Trifiletti, MD, is an International Leader in Radiation Oncology and SRS. His research includes numerous clinical studies involving radiation, surgery, and drug therapies in the treatment of tumors. His short-term research goals focus on describing the impact of radiation on the priming of the brain tumor microenvironment. Discovering the biological underpinnings of radiation priming will allow for novel, “game-changing” cancer therapies, rapid translation to early-stage clinical trials, and, ultimately, improved outcomes in patients with fatal diseases.

Ajay Niranjan, MD, MBA, is a Professor of Neurological Surgery at the University of Pittsburgh. He is the Director of Radiosurgery Research and Associate Director of the Center of Image-Guided Neurosurgery (CIGNS) at the University of Pittsburgh Medical Center. In addition, he is the Director of the UPMC Brain Mapping Center. He serves as the Associate Editor for the Radiosurgery section of Neurosurgery and is Executive Director of the International Radiosurgery Research Foundation (IRRF). He has published more than 350 peer-reviewed papers in journals and edited five books.

Table of Contents:

1. A Short History of Gamma Knife Radiosurgery  2. History of LINAC and Proton Radiosurgery  3. History of CyberKnife Radiosurgery  4. Radiobiology of Stereotactic Radiosurgery  5. Radiology Considerations for Radiosurgery  6. Physics of Stereotactic Radiosurgery  7. Critical Structures and Tolerances for Intracranial Stereotactic Radiosurgery  8. Radiosurgery Pathological Fundamentals  9. Stereotactic Radiosurgery for Arteriovenous Malformations  10. SRS of Cavernomas  11. Stereotactic Radiosurgery for Dural Arteriovenous Fistulas  12. Radiosurgery for meningiomas: an overview of the current status quo  13. Solitary Fibrous Tumor /Hemangiopericytoma  14. SRS for Clinically Nonfunctioning Pituitary Neuroendocrine Tumors  15. Stereotactic Radiosurgery for Functioning Pituitary Neuroendocrine Tumors  16. Stereotactic Radiosurgery for craniopharyngiomas  17. SRS for Chordomas and Chondrosarcomas  18. Stereotactic Radiosurgery as a Preferred Therapeutic Approach for Glomus Tumors  19. Stereotactic Radiosurgery for Hemangioblastoma  20. Stereotactic Radiosurgery for Vestibular Schwannoma  21. Stereotactic Radiosurgery for Nonvestibular Schwannomas  22. Stereotactic Radiosurgery for Facial Neuralgias  23. Radiosurgery for Movement Disorders  24. SRS for OCD  25. Stereotactic Radiosurgery for Hypothalamic Hamartomas  26. Radiosurgical modulation for Epilepsy  27. Radiosurgery for ocular disorders  28. Stereotactic Radiosurgery for Pediatric Brain Tumors and Arteriovenous Malformations  29. Stereotactic Radiosurgery and Hypofractionated Stereotactic Radiotherapy for Gliomas  30. Stereotactic Radiosurgery for the Management of One to Five Brain Metastases  31. Stereotactic Radiosurgery for > 5 Brain Metastases  32. Hypofractionated Stereotactic Radiosurgery for Brain Metastases  33. Stereotactic Radiosurgery and Immunotherapy  34. Repeat Stereotactic Radiosurgery for Brain Metastasis  35. Recognition and Management of Adverse Radiation Effects  36. Application of Artificial Intelligence to Stereotactic Radiosurgery for Intracranial Lesions: Detection, Segmentation, and Outcome Prediction  37. Intracranial Radiosurgery in the World of Large-Scale Brain Networks