Immune and Inflammatory Responses in the Nervous System
Series: Molecular and Cellular Neurobiology;
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Product details:
- Edition number 2
- Publisher OUP Oxford
- Date of Publication 17 October 2002
- ISBN 9780198509806
- Binding Hardback
- No. of pages190 pages
- Size 248x172x15 mm
- Weight 518 g
- Language English
- Illustrations numerous figures and halftones 0
Categories
Short description:
This new edition covers recent advances in understanding immunological and inflammatory responses in the nervous system. This research is driven by the potential to use knowledge of the molecules and mechanisms involved to intervene in, and arrest, neurodegenerative disease processes. Throughout, the emphasis is on the opportunities and ideas for novel treatments.
MoreLong description:
This new edition covers recent advances in understanding immunological and inflammatory responses in the nervous system, research driven by the potential to use knowledge of the molecules and mechanisms involved to intervene in, and arrest, neurodegenerative disease processes.
Immune and Inflammatory Responses in the Nervous System covers developmental aspects of immune/inflammatory responses in the CNS, basic aspects of glial function, as well as inflammatory mediators, their mechanisms of action, clinical importance and sites of infection. There is also coverage of the major diseases of the CNS, including stroke, brain injury, multiple sclerosis and Alzheimer's disease. Throughout, the focus is on the underlying basic neuroscience, clinical relevance and the potential for therapeutic interventions.
This will be an invaluable aid to understanding and improving the diagnosis of neuroimmune diseases and determining therapeutic measures.
The contributors are all leading experts in the field and the content will be of interest to neuroscientists, neurologists, neuropathologists, neurosurgeons and immunologists.
This well-structured and balanced account of our current knowledge of immune and inflammatory aspects of CNS disorders will appeal to researchers and clinicians alike.
Table of Contents:
Developmental influences on inflammation in the brain
Imaging inflammation in the brain
Astrocytic networks and brain injury
Blood-brain barrier and perivascular cells
CNS responses to peripheral insults
Inflammatory events in focal cerebral ischaemia
Cytokines and neurodegeneration
Inflammatory responses to traumatic brain injury: an overview for the millennium
Inflammatory demyelination and axonopathy in the CNS
CNS immune reactions in Alzheimer's disease
Transplantation of neuronal and non-neuronal cells into the brain
