Handbook of Nuclear Medicine and Molecular Imaging for Physicists by Ljungberg, Michael;

Short description:

This state-of-the-art handbook, the second in a series that provides medical physicists with a comprehensive overview into the field of nuclear medicine, focuses on mathematical modelling, dosimetry, and radiation protection.

Long description:

Mathematical modelling is an important part of nuclear medicine. Therefore, several chapters of this book have been dedicated towards describing this topic. In these chapters, an emphasis has been put on describing the mathematical modelling of the radiation transport of photons and electrons, as well as on the transportation of radiopharmaceuticals between different organs and compartments. It also includes computer models of patient dosimetry. Two chapters of this book are devoted towards introducing the concept of biostatistics and radiobiology. These chapters are followed by chapters detailing dosimetry procedures commonly used in the context of diagnostic imaging, as well as patient-specific dosimetry for radiotherapy treatments.

For safety reasons, many of the methods used in nuclear medicine and molecular imaging are tightly regulated. Therefore, this volume also highlights the basic principles for radiation protection. It discusses the process of how guidelines and regulations aimed at minimizing radiation exposure are determined and implemented by international organisations. Finally, this book describes how different dosimetry methods may be utilized depending on the intended target, including whole-body or organ-specific imaging, as well as small-scale to cellular dosimetry.

This text will be an invaluable resource for libraries, institutions, and clinical and academic medical physicists searching for a complete account of what defines nuclear medicine.

• The most comprehensive reference available providing a state-of-the-art overview of the field of nuclear medicine








• Edited by a leader in the field, with contributions from a team of experienced medical physicists, chemists, engineers, scientists, and clinical medical personnel








• Includes the latest practical research in the field, in addition to explaining fundamental theory and the field's history

Table of Contents:

Contents

Preface...............................................................................................................................vii

Editor..................................................................................................................................ix

Contributors.......................................................................................................................xi

Chapter 1 Introduction to Biostatistics..........................................................................1

Chapter 2 Radiobiology....................................................................................................17

Chapter 3 Diagnostic Dosimetry.............................................................................................33

Chapter 4 Time- activity Curves: Data, Models, Curve Fitting, and Model Selection..........................69

Chapter 5 Tracer Kinetic Modelling and Its Use in PET Quantification..............................................83

Chapter 6 Principles of Radiological Protection in Healthcare..........................................................101

Chapter 7 Controversies in Nuclear Medicine Dosimetry..................................................................115

Chapter 8 Monte Carlo Simulation of Photon and Electron Transport in Matter..............................123

Chapter 9 Patient Models for Dosimetry Applications..........................................................141

Chapter 10 Patient- specific Dosimetry Calculations.............................................................155

Chapter 11 Whole- body Dosimetry..................................................169

Chapter 12 Personalized Dosimetry in Radioembolization........................................................................................183

Remco Bastiaannet and Hugo W.A.M. de Jong

Chapter 13 Thyroid Imaging and Dosimetry..........................................................................207

Chapter 14 Bone Marrow Dosimetry........................................................................................223

Chapter 15 Cellular and Multicellular Dosimetry...................................................................235

Chapter 16 Alpha- particle Dosimetry................................................................267

Chapter 17 Staff Radiation Protection........................................................................275

Chapter 18 IAEA Support to Nuclear Medicine...........................................................293

Gian Luca Poli