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  • Evolution and Selection of Quantitative Traits

    Evolution and Selection of Quantitative Traits by Walsh, Bruce; Lynch, Michael;

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      • Publisher's listprice GBP 160.00
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    72 240 Ft

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    Estimated delivery time: In stock at the publisher, but not at Prospero's office. Delivery time approx. 3-5 weeks.
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    Product details:

    • Publisher OUP Oxford
    • Date of Publication 12 July 2018

    • ISBN 9780198830870
    • Binding Hardback
    • No. of pages1496 pages
    • Size 284x223x62 mm
    • Weight 3878 g
    • Language English
    • 60

    Categories

    Short description:

    This is the second volume in a planned trilogy that summarises the modern field of quantitative genetics, informed by empirical observations from wide-ranging fields (agriculture, evolution, ecology, and human biology) as well as population genetics, statistical theory, mathematical modeling, genetics, and genomics.

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    Long description:

    Quantitative traits-be they morphological or physiological characters, aspects of behavior, or genome-level features such as the amount of RNA or protein expression for a specific gene-usually show considerable variation within and among populations. Quantitative genetics, also referred to as the genetics of complex traits, is the study of such characters and is based on mathematical models of evolution in which many genes influence the trait and in which non-genetic factors may also be important.

    Evolution and Selection of Quantitative Traits presents a holistic treatment of the subject, showing the interplay between theory and data with extensive discussions on statistical issues relating to the estimation of the biologically relevant parameters for these models. Quantitative genetics is viewed as the bridge between complex mathematical models of trait evolution and real-world data, and the authors have clearly framed their treatment as such. This is the second volume in a planned trilogy that summarizes the modern field of quantitative genetics, informed by empirical observations from wide-ranging fields (agriculture, evolution, ecology, and human biology) as well as population genetics, statistical theory, mathematical modeling, genetics, and genomics. Whilst volume 1 (1998) dealt with the genetics of such traits, the main focus of volume 2 is on their evolution, with a special emphasis on detecting selection (ranging from the use of genomic and historical data through to ecological field data) and examining its consequences.

    ...the authors have done an admirable job at integrating the newest results to provide an unusually current and comprehensive guide. It is hard to imagine that anyone publishing in this area could make the case that they have added to what is known without consulting this wonderful book.

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    Table of Contents:

    Preface
    I
    Introduction
    Changes in quantitative traits over time
    II
    Evolution at one and two loci
    Neutral evolution in one- and two-locus systems
    The genetic effective size of a population
    The nonadaptive forces of evolution
    The population genetics of selection
    Theorems of natural selection: Results of Price, Fisher, and Robertson
    Interaction of selection, mutation, and drift
    Hitchhiking and selective sweeps
    Using molecular data to detect selection: Signatures from recent single events
    Using molecular data to detect selection: Signatures from multiple historical events
    III
    Drift and quantitative traits
    Changes in genetic variance induced by drift
    The neutral divergence of quantitative traits
    IV
    Short-term response on a single character
    Short-term changes in the mean: 1. The breeder's equation
    Short-term changes in the mean: 2. Truncation and threshold selection
    Short-term changes in the mean: 3. Permanent versus transient response
    Short-term changes in the variance: 1. Changes in the additive variance
    Short-term changes in the variance: 2. Changes in environmental variance
    Analysis of short-term selection experiments: 1. Least-squares approaches
    Analysis of short-term selection experiments: 2. Mixed-model and bayesian approaches
    Selection response in natural populations
    V
    Selection in structured populations
    Family-based selection
    Associative effects: Competition, social interactions, group and kin selection
    Selection under inbreeding
    VI
    Population-genetic models of trait response
    The infinitesimal model and its extensions
    Long-term response: 1. Deterministic aspects
    Long-term response: 2. Finite population size and mutation
    Long-term response: 3. Adaptive walks
    Maintenance of quantitative genetic variation
    VII
    Measuring selection on traits
    Individual fitness and the measurement of univariate selecton
    Measuring multivariate selection
    VIII
    Appendices
    Diffusion theory
    Introduction to Bayesian Analysis
    Markov Chain Monte Carlo and Gibbs sampling
    Multiple comparisons: Bonferroni corrections, false-discovery rates, and meta-analysis
    The geometry of vectors and matrices: Eigenvalues and eigenvectors
    Derivatives of vectors and vector-valued functions
    Literature Cited
    Author Index
    Organism and Trait Index
    Subject Index

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