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    Development of T Cell Immunity

    Development of T Cell Immunity

    Series: Progress in Molecular Biology and Translational Science; 92;

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      • Publisher's listprice EUR 137.00
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        53 512 Ft (50 964 Ft + 5% VAT)
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    Product details:

    • Publisher Elsevier Science
    • Date of Publication 28 October 2010

    • ISBN 9780123812841
    • Binding Hardback
    • No. of pages342 pages
    • Size 228x152 mm
    • Weight 610 g
    • Language English
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    Long description:

    T cells belong to a group of white blood cells called lymphocytes and play a large role in the immune response. An increased understanding of T cell immunity will provide new insights into the etiology of human autoimmune disease such as diabetes.

    This volume reviews the latest developments and discusses the evolution of T cell immunity, thymic requirements, and how to prevent T cell-dependent autoimmunity.

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    Table of Contents:

    "

    Development of T cell immunity

    1. The development of T cell immunity - Adrian Liston
    2. The evolution of T cell immunity

    3. Genome duplication and T cell immunity - Masanori Kasahara

    • Questions arising from ""Genome duplication and T cell immunity"" - Claude Perreault
    • Response to questions - Masanori Kasahara

    1. The origin and role of MHC class I-associated self peptides - Claude Perreault

    • Questions arising from ""The origin and role of MHC class I-associated self peptides"" - Masanori Kasahara
    • Response to questions - Claude Perreault

    Thymic requirements for T cell immunity

    1. Transcriptional regulation of thymus organogensis and thymic epithelial cell differentiation - Nancy Manley and Brian Condie
    2. Early T cell differentiation: lessons from T-cell acute lymphoblastic leukemia - Cedric S Tremblay, Thu Hoang and Trang Hoang
    3. T cell immunity in the periphery

    4. Lymphoid tissue inducer cells and the evolution of CD4 dependent high affinity antibody responses - Peter J L Lane, Fiona M McConnell, David Withers, Fabrina Gaspal, Manoj Saini and Graham Anderson

    • Commentary on ""Lymphoid tissue inducer cells and the evolution of CD4 dependent high affinity antibody responses"" - Mark Coles, Dimitri Kioussis and Henrique Veiga-Fernandes

    1. Cellular and Molecular Requirements in Lymph Node and Peyer's Patch Development - Mark Coles, Dimitri Kioussis and Henrique Veiga-Fernandes
    2. T follicular helper cells during Immunity and Tolerance - Michelle A. Linterman and Carola G. Vinuesa
    3. Preventing T cell-dependent autoimmunity

    4. Thymic selection and lineage commitment of CD4+Foxp3+ regulatory T cells - Paola Romagnoli and Joost P.M. van Meerwijk
    5. Molecular Mechanisms of Regulatory T cell Development and Suppressive Function - Jeong M. Kim

      • Is Foxp3 the master regulator of regulatory T cells? - Adrian Liston
    "

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