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46 819 Ft
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Product details:
- Publisher OUP Oxford
- Date of Publication 9 November 2000
- ISBN 9780199638574
- Binding Paperback
- No. of pages224 pages
- Size 246x188x13 mm
- Weight 514 g
- Language English
- Illustrations line figures 0
Categories
Short description:
The study of cytokines is central to biomedical research as they are involved in regulating development, tissue repair, haemopoiesis, inflammation, and the immune response. The field has grown so much in the past 5 years that the third edition has expanded into two volumes, one concentrating on molecular biology and the other on cellular biology.
MoreLong description:
Cytokine Molecular Biology concentrates on molecular biology techniques for the study of cytokines, cytokine receptors, and cytokine driven processes. Updated topics from the previous edition are: the cloning and expressing cytokine genes;; the detection of cytokine mRNA; receptor binding studies; the PC-specific phosphslipase C and sphingomylinases. In addition, new topics covered are the purification, sequencing, and synthesis of cytokines; studying
cytokine gene polymorphisms; the use of proteomics in cytokine research; and the Jak/STAT and MAPK signalling pathways. Written by experts in the field, Cytokine Molecular Biology and Cytokine Cellular Biology form a comprehensive and essential guide to cytokine research.
Table of Contents:
Cloning and expression of cytokine genes
Methods for studying cytokine gene polymorphisms
Northern analysis, RT-PCR, Rnase protection, cDNA array systems and in situ hybridization detection of cytokine messenger RNA
Purification, sequencing and synthesis of cytokines and chemokines
Receptor binding studies
Cytokine signalling
Cytokine receptor signalling pathways: PC-specific phospholipase C and sphingomyelinases
Proteome analysis in cytokine research
Conditional and fixed cytokine gene modification in transgenic and mutant mice
