Cut-and-Paste Genetics
A CRISPR Revolution
- Publisher's listprice GBP 35.00
-
16 721 Ft (15 925 Ft + 5% VAT)
The price is estimated because at the time of ordering we do not know what conversion rates will apply to HUF / product currency when the book arrives. In case HUF is weaker, the price increases slightly, in case HUF is stronger, the price goes lower slightly.
- Discount 20% (cc. 3 344 Ft off)
- Discounted price 13 377 Ft (12 740 Ft + 5% VAT)
Subcribe now and take benefit of a favourable price.
Subscribe
16 721 Ft
Availability
printed on demand
Why don't you give exact delivery time?
Delivery time is estimated on our previous experiences. We give estimations only, because we order from outside Hungary, and the delivery time mainly depends on how quickly the publisher supplies the book. Faster or slower deliveries both happen, but we do our best to supply as quickly as possible.
Product details:
- Publisher Bloomsbury Publishing (UK)
- Date of Publication 15 September 2021
- Number of Volumes Hardback
- ISBN 9781786614377
- Binding Hardback
- No. of pages224 pages
- Size 237.74x161.8x18.288 mm
- Weight 449 g
- Language English
- Illustrations 3 b/w illustrations; 1 table Illustrations, unspecified 187
Categories
Long description:
The emergence of CRISPR/Cas9 technology has revolutionized gene editing. The Nobel prize for chemistry was awarded to Emmanuelle Charpentier and Jennifer Doudna, the scientists responsible for its discovery, in 2020 and it is considered the frontier of sophisticated medical science. This technology contains the promise that both gene therapy and eugenic control of human evolution is possible, even plausible, in our near future.
This book looks at these developements in the context of the history of previous social and scientific attempts at genetic editing, and explores the policy and ethical challenges they raise. It presents the case for altering the human germ-line (which contains and controls hereditary genetic information) to eliminate a large number of genetic diseases controlled by a single or few genes, while pointing out that gene therapy is likely to be ineffective for diseases with more complex causes. In parallel it explores the possibility of genetic enhancement in a set of case studies. But it also argues that, in general, genetic enhancement is ethically problematic and should be approached with caution.
Given the success of CRISPR/Cas9 gene editing, and the explosion of related techniques, in practice it would be virtually impossible to ban germ-line editing in our future. A more useful goal is to put regulation in place, with oversight that represents the interests of society. That, in turn, requires an informed public discussion of these issues, which is the intention of this book.
Table of Contents:
Preface
1.Breeding a Perfect Society
Beginnings: Davenport and eugenics in the United States * IQ and involuntary sterilization * Genetics against eugenics * Exporting sterilization * The Watson scandal * Davenport's dreams today
2.Molecular Diseases, Elusive Treatments
The molecularization of biology * Molecular diseases * But no molecular medicine
*Dreams of editing genes * Followed by stunning failure * Recombinant DNA made no difference * Gene editing BC
3.What Good Was the Human Genome Project?
The sequence revealed * Common diseases and common variants * Medical irrelevance of the sequence * Critiques of the HGP, past and present * Evolution and architecture of the genome * Evolutionary contingency
4.The CRISPR Revolution
The CRISPR structure emerges * Its function is decoded * The mechanism of immunity * Onward to gene editing * The delivery problem * Ubiquitous CRISPR
5.Inevitable Eugenics?
Eugenics in the news * What is eugenics? * Defining eugenics * A working definition * Inescapable eugenics? * Matters of ethics
6.Eliminating Genetic Diseases
The long reach of Huntington's disease * The He Jiankui affair * The ethics of human germ-line intervention * The limits of current science * Gene specificity and Lenin's brain * A policy proposal * Proceed with caution * Liberal and moderate eugenics
7.Designer Baby Delusions
Why not genetic enhancement? * The normal and the enhanced * Liberal eugen- ics and genetic enhancement * Rationality of genetic enhancement * Planned human obsolescence * Where is the science? The case of intelligence * Genomics and IQ * What about physical traits * Genetic reductionism * Contextual developmental construction * What is perfection?
8.A CRISPR Future
Editing the human germ-line * Gene drives * The ethics of promoting extinction
*Biosecurity * CRISPR without the hype
HIV/AIDS and HIV/AIDS-Related Terminology: A Means of Organizing the Body of Knowledge
Handbook of Moral Development
62 107 HUF
55 897 HUF
