Cell Signalling
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Product details:
- Edition number 3
- Publisher OUP Oxford
- Date of Publication 21 January 2010
- ISBN 9780199232109
- Binding Paperback
- No. of pages368 pages
- Size 245x188x16 mm
- Weight 799 g
- Language English
- Illustrations 107 line illustrations 0
Categories
Short description:
A carefully structured introduction to this intricate subject, Cell Signalling introduces those conserved features that underlie many different extra- and intracellular signalling systems. After exploring the key components of signalling mechanisms it goes on to examine how signalling pathways are constructed from those components.
MoreLong description:
Signalling within and between cells is an essential part of many biological processes, from the development of the body, to the activity of our immune system. Recent advances in molecular cell biology have allowed us to identify the components of signalling pathways, and examine how they interact to form the carefully orchestrated and controlled networks upon which the complexity of a living organism is built.
Starting with an overview of cell signalling and highlighting its importance in many biological systems, the book goes on to explore the key components of extracellular and intracellular signalling mechanisms, before examining how these components come together to create signalling pathways, which are so crucial to the survival of many living organisms.
Cell Signalling presents a carefully structured introduction to this intricate subject, introducing those conserved features that underlie many different extra- and intracellular signalling systems.
? A focus on generic components of extra- and intracellular signalling pathways allows the student to gain a thorough understanding of the underlying principles of cell signalling before exploring how the individual components interact to form complex signalling pathways
? The ubiquity of key signalling mechanisms is highlighted, enabling students to see how similar mechanisms are conserved and harnessed in many different biological systems
? The student is directed to carefully chosen further reading articles, allowing them to readily explore key topics in more detail
Online Resource Centre
The Online Resource Centre to accompany Cell Signalling features:
For students:
? Links to useful websites
? Hyperlinked references
For Lecturers:
? All figures from the book
Complexity and specificity are the hallmarks of cell signalling, yet Hancock in this third edition has gone a long way to simplify these complicated processes. His signalling examples are clever and well-conceived, his writing descriptive and his passion for his subject infectious ... this is marvellous value for money and is a worthy companion to an undergraduate/postgraduate reference libary.
Table of Contents:
Figure Legends
Preface
Abbreviations
Part I: An overview of cell signalling
Aspects of cellular signalling
Pathways are the key to signalling
A look at some of the history and techniques of cell signalling
Part II: The Components that compromise signalling pathways
Extracellular signals: hormones, cytokines and growth factors
Detection of extracellular signals: the role of receptors
Protein phosphorylation, kinases and phosphatases
Cyclic nucleotides, cyclases and G proteins
Inositol phosphate metabolism and roles of membrane lipids
Intracellular calcium: Its control and role as an intracellular signal
Reactive oxygen species, reactive nitrogen species and redox signalling
Part III: Selected examples of signalling pathways and events
Insulin and the signal transduction cascades it invokes
Perception of the environment
Signalling in development and for the regulation of gene expression
Life, death and apoptosis
Part IV: Final thoughts
Cell Signalling: importance, complexity, and future
Index
