Biomechanics and Mechanobiology of Bone
From Model to Patient
Series: Biomechanics of Living Organs;
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90 615 Ft (86 300 Ft + 5% VAT)
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Product details:
- Publisher Elsevier Science
- Date of Publication 1 June 2026
- ISBN 9780443267390
- Binding Hardback
- No. of pages550 pages
- Size 235x191 mm
- Weight 450 g
- Language English 700
Categories
Long description:
Biomechanics and Mechanobiology of Bone: From Model to Patient provides readers with a comprehensive overview of the modelling and assessment of bone biomechanics. It addresses topics such as biosubstitutes and bone implants from the point of view of design, properties, computational modeling, and choice of biomaterials. It concentrates on the biomechanics and mechanobiology modeling approaches of bone, including biological models, multiphysical approaches, surface and volumetric growth models, and bone fluid flow models. This is augmented by case studies and examples of models for computer-aided diagnosis, treatment, and monitoring of bone diseases. Readers are introduced to bone physiology, adaptation, and disease, including cellular aspects at the root of bone mechanotransduction and leading to bone growth and remodeling, and management of diseases. Chapters also cover the mechanical, multiphysical multiscale properties of bone and constitutive laws including bone viscoelasticity, poroelasticity, bone damage, fatigue and fracture, as well as measurement techniques of bone properties.
MoreTable of Contents:
PART 1: Bone Physiology, Adaptation and Disease
1. Anatomy and Physiology of Bone
2. Collagen & Bone Mineralization
3. Bone Cells, roles and functions
4. Mechanosensing and Mechanotransduction /Experiments on Cells Mechanosensation and Mechanotransduction
5. Growth, Development and Bone Adaptation
6. Bone Quantity and Quality
7. Bone Diseases and mechanical competence
8. Treatment and Management of Bone Diseases
PART 2: Mechanical, Multiphysical Properties of Bone and Constitutive Laws
9. Poromechanics of Bone
10. Mechanics of Bone Through the Length Scales
11. Experimental Bone Mechanics (Mechanical Tests - Bioreactors) / Elastic Properties of Cortical and Cancellous Bone Tissue
12. Fabric Tensor - Constitutive Models of Bone Tissue / Assessment of Cancellous Bone Architecture
13. Viscoelastic Properties of Cortical and Cancellous Bone
14. Bone Damage and Fatigue
15. Bone Strength
16. Bone Fracture Toughness
17. Energy Absorption of bone
PART 3: Biosubstitutes and Bone Implants
18. Biomaterials in Bone Bioengineering
19. Biomaterials for Graft Procedures: Overview and Perspectives
20. Bone Biosubstitutes and Implants: Design, Properties and Production
21. Numerical Simulations of Bone Implants Behavior
22. Case Studies of Bone Replacement Scaffolds
PART 4: Biomechanics and Mechanobiology Modeling
23. Bone Adaptation Models: from Wolff’s law to Modern Views
24. Volumetric and Surface Growth Models
25. Shape and topology Optimization approaches
26. Bone Fluid Flow Models
27. Biological Models of Mechanosensing and Mechanotransduction
28. Multiphysical Aspects of Bone Remodeling and mechanostransduction - Modeling approaches
29. Numerical Simulations of Bone Adaptation Throughout the Scales
30. Frontiers of Bone Biomechanics: Overview of Challenges
