Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging
Volume 12
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Product details:
- Publisher Elsevier Science
- Date of Publication 29 September 2017
- ISBN 9780128121467
- Binding Hardback
- No. of pages622 pages
- Size 234x190 mm
- Weight 2010 g
- Language English 0
Categories
Long description:
Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 12 discusses and details almost all aspects of the autophagy machinery in the context of health, cancer and other pathologies. Autophagy is more widely accepted as beneficial given its role in eliminating 'toxic assets' and promoting cell viability, hence, it has emerged as a new and potent modulator of disease progression that is both scientifically intriguing and clinically relevant. As the latest release in the Autophagy book series, users will find a detailed explanation of the role of molecular mechanisms.
MoreTable of Contents:
I. MOLECULAR MECHANISMS
1. Overview of Autophagyï¿1⁄2
2. The Role of Autophagy in Ageing: Molecular Mechanisms
3. The Role of p62 in Aggregopathies
4. Role of Autophagy in the Transition from Monocyte to Differentiation
5. CDC48 AAA ATPASE Regulates Protein Dynamics and Turnover in Mitochondria
6. Autophagy in Plasma Cellsï¿1⁄2
7. Loss of Pink1 or Parkin Function Results in a Progressive Loss of Mitochondrial Function
8. Role of the Transcription Factor IRF-1 in Regulating Autophagy in Lipopolysaccharide Stimulated Macrophages
9. mTOR: The Alpha and Omega of Autophagy Regulation
10. ER-phagy in Starvation, ER Stress, and Quality Control
11. Role of Autophagy Inhibition in Tumor Proliferative Arrest
12. Survival at the Brink: Chromatin Autophagy of Tumour Cells in Response to Genotoxic Challenge
13. Loss of Autophagy in Hypothalmic Neurons May be Involved in the Pathogenesis of Obesity
14. Defective Autophagy in Mesenteric Fat Tissue Maintains Inflammation in Crohn's Disease
15. Autophagy Regulates Inflammatory Responses in Antigen Presenting Cells: Underlying Mechanismsï¿1⁄2
16. ï¿1⁄2Autophagy Accompanies Inflammasome Activation Moderating Inflammation by Eliminating Active Inflammasomes
17. Autophagy, Inflammation, and Breast Cancer Risk
18. AMBRA-Mediated regulation of V-MYC and its Relevance to Cancerï¿1⁄2
19. The Delicate Balance of Autophagy in Neurodegeneration
20. Silibinin Protects Uvb-Irradiated Skin by Balancing Apoptosis and Autophagy in Epidermis and Dermis
21. Role of Autophagy Activation in Alleviating Alcohol Neurotoxicity
22. Lipopolysaccharide-Enhanced Bactericidal Activity is Mediated by Induction of the Autophagosomal Process
23. Role of Autophagy in Liver Regeneration
24. A Dual Role of a Soluble N-Ethylmaleimide Sensitive Factor-Attachment Protein Alpha (?-Snap) in the Regulation of Autophagyï¿1⁄2
25. TRAIL Induces Autophagic Protein Cleavage in Melanoma Cells