Advances in Drug Discovery for Alzheimer’s Disease
Series: Topics in Medicinal Chemistry;
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- Discount is valid until: 30 June 2026
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Product details:
- Publisher Springer Nature Switzerland
- Date of Publication 30 June 2026
- ISBN 9783032287298
- Binding Hardback
- No. of pages266 pages
- Size 235x155 mm
- Language English
- Illustrations VII, 266 p. 50 illus., 25 illus. in color. 700
Categories
Long description:
"
This book reviews recent advances in drug discovery for Alzheimer’s disease, focusing on major targets and approaches. Topics include approaches to targeting—directly or indirectly—the two proteins that pathologically accumulate in the brain in Alzheimer’s disease, the amyloid β-peptide and the microtubule-associated protein tau, which remain top targets for disease prevention and treatment. A chapter on the emerging area of AI approaches to drug repurposing and discovery will also be included, with examples of the use of big data to identify novel therapeutic modalities. An overview chapter will put these approaches into broader context; describe other important and emerging approaches, targets, and drug candidates; and provide a critical assessment of the potential of these approaches to lead to effective therapeutics. This book is particularly appealing to researchers, clinicians, and students in the fields of medicinal chemistry, neuroscience, pharmacology, and biomedical sciences, as well as anyone interested in the latest advancements in Alzheimer’s disease research and drug discovery.
" MoreTable of Contents:
Drug Discovery for Alzheimer's Disease: Current Status.- Recent Advances in the Development of γ-Secretase Modulators to Treat Alzheimer’s Disease.- Beta-Secretase Inhibitors.- Tau Aggregation Inhibitors.- The Role of Molecular Chaperones in Tau Proteostasis: Potential Therapeutic Opportunities in Tauopathies.- Targeting Caspase-2 for the Treatment of Dementia.- The Role of Artificial Intelligence for Drug Repurposing in Alzheimer’s Disease.
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