Adjustment Cord Theory
Untangling Complex Disease Networks
-
GET 12% OFF
- Publisher's listprice EUR 139.09
-
57 687 Ft (54 940 Ft + 5% VAT)
The price is estimated because at the time of ordering we do not know what conversion rates will apply to HUF / product currency when the book arrives. In case HUF is weaker, the price increases slightly, in case HUF is stronger, the price goes lower slightly.
- Discount 12% (cc. 6 922 Ft off)
- Discounted price 50 765 Ft (48 347 Ft + 5% VAT)
50 765 Ft
Availability
Not yet published.
Why don't you give exact delivery time?
Delivery time is estimated on our previous experiences. We give estimations only, because we order from outside Hungary, and the delivery time mainly depends on how quickly the publisher supplies the book. Faster or slower deliveries both happen, but we do our best to supply as quickly as possible.
Product details:
- Publisher Springer Nature Singapore
- Date of Publication 16 April 2026
- ISBN 9789819576449
- Binding Paperback
- No. of pages72 pages
- Size 203x127 mm
- Language English
- Illustrations IX, 72 p. 3 illus., 2 illus. in color. 700
Categories
Long description:
"
This book sheds new light on the challenge of treating multifaceted chronic diseases with targeted therapies. By reframing disease networks as helices of converging vectors, it introduces the concept of the ""adjustment cord""—a single, central point whose modulation can collapse the pathological spiral. This approach offers a fresh perspective on how to achieve effective therapeutic outcomes with minimal off-target effects.
The chapters cover topics such as the visual metaphor of the tsuzumi cord and spiral convergence, providing a philosophical and strategic framework for targeted intervention. Through detailed case studies in skin diseases like atopic dermatitis and psoriasis, the book illustrates how blocking specific cytokine axes can interrupt self-amplifying loops and restore homeostasis. It also explores the generalizability of this model across different organ systems, extending its relevance to internal diseases and systemic conditions.
Readers will discover a wealth of insights supported by clinical trial data, mechanistic insights, and computational methods. The book invites readers to think through critical questions such as how to identify the most impactful node in a complex network and how to prevent compensatory bypass pathways. By offering a practical roadmap for network-based target identification, the book promises to guide new drug development and improve patient outcomes.
Adjustment Cord Theory - Untangling Complex Disease Networks is indispensable for researchers, clinicians, and pharmaceutical professionals involved in precision medicine and targeted therapy development. Its cross-disciplinary appeal extends to dermatology, rheumatology, and beyond, making it a valuable resource for anyone interested in the future of medical intervention.
" MoreTable of Contents:
"
Chapter 1: Why Complex Diseases Resist Simplification.- Chapter 2: Theoretical Foundations of Adjustment Cord Theory.- Chapter 3: Three Fundamental Morphologies of Disease Expression.- Chapter 4: From Morphology to Structure.- Chapter 5: Defining the Adjustment Cord.- Chapter 6: Dynamic Reconfiguration of Tension Networks.- Chapter 7: Intervention Through Adjustment Cords.- Chapter 8: Structural Motifs, Generality, and Transferability.- Chapter 9: Methodological Implications.- Chapter 10: Designing for Structured Complexity.
" More
