A Pharmacology Primer
Techniques for More Effective and Strategic Drug Discovery
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Product details:
- Edition number 5
- Publisher Elsevier Science
- Date of Publication 5 November 2018
- ISBN 9780128139578
- Binding Paperback
- No. of pages488 pages
- Size 276x215 mm
- Weight 1220 g
- Language English 0
Categories
Long description:
A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Fifth Edition features the latest ideas and research regarding the application of pharmacology to the process of drug discovery. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for all those involved in drug discovery. This updated edition has been thoroughly revised to include material on quantifying drug efficacy through bias and cluster analysis, the impact of molecular dynamics and protein structural analysis, the real time kinetic analysis of drug effect, virtual screening for new drug chemical scaffolds, and much more.
With full color illustrations and new examples throughout, this book remains a top reference for all industry and academic scientists that is also ideal for students directly involved in drug discovery or pharmacologic research.
MoreTable of Contents:
1. What Is Pharmacology?2. How Different Tissues Process Drug Response 3. Drug-Receptor Theory4. Pharmacological Assay Formats: Binding5. Agonists: The Measurement of Affinity and Efficacy in Functional Assays6. Orthosteric Drug Antagonism7. Allosteric Modulation8. The Optimal Design of Pharmacological Experiments9. Pharmacokinetics10. Safety Pharmacology11. The Drug Discovery Process12. Statistics and Experimental Design13. Selected Pharmacological Methods14. Exercises in Pharmacodynamics and Pharmacokinetics
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