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    A Patient's Guide to Clinical Trials: Navigating the Promise and Pitfalls of Experimental Treatments

    A Patient's Guide to Clinical Trials by Palma, Jose-Alberto;

    Navigating the Promise and Pitfalls of Experimental Treatments

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    Product details:

    • Publisher Bloomsbury Publishing (UK)
    • Date of Publication 30 April 2026

    • ISBN 9798881842475
    • Binding Hardback
    • No. of pages296 pages
    • Size 218x146x26 mm
    • Weight 491 g
    • Language English
    • 700

    Categories

    Short description:

    Every year, millions of people face life-threatening illnesses for which effective treatments are limited or nonexistent.

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    Long description:

    Every year, millions of people face life-threatening illnesses for which effective treatments are limited or nonexistent.

    Yet only a small fraction of patients participates in clinical trials, even though these studies are vital to developing new therapies. Fewer than 8 percent of adult cancer patients take part in these trials, with even lower rates among Black and Hispanic populations. This gap is not merely due to a lack of interest; the clinical trial process can be daunting, often leaving patients and their families uninformed, unprepared and overwhelmed.

    This book offers a much-needed, clear, balanced, and comprehensive guidance at a moment when patient-centered care has never been more important. It demystifies how trials work, what patients can expect, and how to weigh the promise of cutting-edge treatments against the challenges and potential risks involved. It simultaneously empowers patients and caregivers to make informed decisions, turning a process that can feel intimidating into one that is understandable, navigable, and ultimately hopeful.

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    Table of Contents:

    Why I Wrote This Book
    Introduction
    Chapter 1. Understanding Clinical Trials: A Primer
    What is a Clinical Trial?
    Overview of the Clinical Trial Phases
    Must All Drugs Complete Every Phase?
    Overview of the Drug Development Process
    Who is Responsible and Pays for a Clinical Trial?
    Who Oversees Clinical Trials?
    Ten Clinical Trials Myths
    Chapter 1 Highlights

    Chapter 2. Should You Join a Clinical Trial?
    The Good, The Bad, and The Ugly: Real-World Cases of Extreme Success or Failure
    Why People Participate in Clinical Trials
    Understanding Potential Clinical Trial Risks and Burdens
    Placebo, Blinding, Randomization, and Other Uncertainties
    The Three Most Important Questions to Ask Yourself
    How to Discuss Clinical Trials with Your Doctor
    Chapter 2 Highlights

    Chapter 3. Where to Start: Finding Clinical Trials
    How to Search for Clinical Trials
    A Step-by-Step Guide to Using ClinicalTrials.gov
    Can Artificial Intelligence Chatbots Help to Find Clinical Trials?
    Other Resources and Websites for Finding Trials
    When No Trials Are Available
    Is It a Clinical Trial or a Scam?
    Chapter 3 Highlights

    Chapter 4. Choosing the Right Clinical Trial
    Key Questions Before Selecting a Trial
    Ranking Clinical Trials: How To Prioritize Your Options
    Learning More About the Experimental Therapy and Its Target
    Becoming a Participant in a Clinical Trial
    What Happens if a Trial is Delayed or Canceled?
    Chapter 4 Highlights

    Chapter 5. Inside the Clinical Trial: What to Expect
    The Informed Consent Is the First Step of the Screening
    Understanding Trial Criteria and Confirming Eligibility
    What is a Screen Failure
    After the Screening: Randomization and Additional Visits
    Participants' Responsibilities and Commitment
    What Happens if You Want to Stop Your Participation in a Trial?
    Chapter 5 Highlights

    Chapter 6. Practical and Emotional Support During the Trial
    Financial and Medical Insurance Implications
    Travel and Logistics Planning
    Balancing Work, Family, and Trial Commitments
    How Caregivers Can Support Trial Participants
    Building a Support Network
    What to Do When Things Go Wrong
    Chapter 6 Highlights

    Chapter 7. After The Trial: What Comes Next
    What Happens at the End of Study Visit?
    Open-Label Extension
    Pros and Cons of OLE Participation
    What if an Open-Label Extension is Not Available?
    Do Clinical Trial Participants Feel Valued?
    Accessing Clinical Trial Data and Results
    Handling Negative Clinical Trial Results
    Integrating Trial Results into Your Healthcare
    Support Systems After the Trial
    Chapter 7 Highlights

    Chapter 8. Addressing Unique Populations in Clinical Trials
    Clinical Trials in Children
    Clinical Trials in Other Vulnerable Populations
    Clinical Trials for Rare Diseases
    Increasing Representation in Clinical Trials
    Chapter 8 Highlights

    Chapter 9. The Future of Clinical Trials: Innovation and Empowerment
    How Could Drug Development and Clinical Trials Be Improved?
    Decentralized Clinical Trials: Clinical Trials at (or Near) Home
    AI and Digital Technologies
    Could We Ever Get Rid of Clinical Trials?
    The Most Important Innovation: Empowered Participants
    Chapter 9 Highlights

    Epilogue. Considering Clinical Trials: A Leap of Hope
    Acknowledgments
    Resources for Further Information
    Glossary
    Bibliography
    About the Author

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