Single-cell Sequencing and Methylation: Methods and Clinical Applications
 
A termék adatai:

ISBN13:9789811544934
ISBN10:981154493X
Kötéstípus:Keménykötés
Terjedelem:247 oldal
Méret:254x178 mm
Súly:685 g
Nyelv:angol
Illusztrációk: 3 Illustrations, black & white; 114 Illustrations, color
239
Témakör:

Single-cell Sequencing and Methylation

Methods and Clinical Applications
 
Kiadás sorszáma: 1st ed. 2020
Kiadó: Springer
Megjelenés dátuma:
Kötetek száma: 1 pieces, Book
 
Normál ár:

Kiadói listaár:
EUR 160.49
Becsült forint ár:
66 226 Ft (63 072 Ft + 5% áfa)
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52 980 (50 458 Ft + 5% áfa )
Kedvezmény(ek): 20% (kb. 13 245 Ft)
A kedvezmény érvényes eddig: 2024. június 30.
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  példányt

 
Rövid leírás:

With the rapid development of biotechnologies, single-cell sequencing has become an important tool for understanding the molecular mechanisms of diseases, defining cellular heterogeneities and characteristics, and identifying intercellular communications and single-cell-based biomarkers. Providing a clear overview of the clinical applications, the book presents state-of-the-art information on immune cell function, cancer progression, infection, and inflammation gained from single-cell DNA or RNA sequencing. Furthermore, it explores the role of target gene methylation in the pathogenesis of diseases, with a focus on respiratory cancer, infection and chronic diseases. As such it is a valuable resource for clinical researchers and physicians, allowing them to refresh their knowledge and improve early diagnosis and therapy for patients.

Hosszú leírás:

With the rapid development of biotechnologies, single-cell sequencing has become an important tool for understanding the molecular mechanisms of diseases, defining cellular heterogeneities and characteristics, and identifying intercellular communications and single-cell-based biomarkers. Providing a clear overview of the clinical applications, the book presents state-of-the-art information on immune cell function, cancer progression, infection, and inflammation gained from single-cell DNA or RNA sequencing. Furthermore, it explores the role of target gene methylation in the pathogenesis of diseases, with a focus on respiratory cancer, infection and chronic diseases. As such it is a valuable resource for clinical researchers and physicians, allowing them to refresh their knowledge and improve early diagnosis and therapy for patients.

Tartalomjegyzék:

Values of single-cell sequencing and methylation in molecular diagnosis and therapy.- Single-cell sequencing in human diseases.- Single-cell sequencing of T cell receptors: A perspective on the technological development and translational application.- DNA Methylation in pulmonary fibrosis.- Molecular regulation and clinical significance of caveolin-1 methylation in chronic lung diseases.- Research advances on DNA methylation in idiopathic pulmonary fibrosis.- DNA Methylation in Chronic Obstructive Pulmonary Disease.- Single cell sequencing: a new dimension in cancer diagnosis.- The Role of Methylation in the CpG Island of the ARHI Promoter Region in Cancers.- Clinical Significance of P16 Gene Methylation in Lung Cancer.- Application of single-cell RNA sequencing in pancreatic cancer and the endocrine pancreas.- Single Cell Sequencing in GU Malignancies.- PI3K Isoform-Selective Inhibitors in Cancer.- Single cell RNA sequencing in human disease: Renal, pancreatic, and viral diseases.- Single-cell sequencing in human genital infections.- PI3kinase Inhibitors in Thrombosis and Cardiovascular Disease.- Use of single-cell microfluidic technology towards therapeutic antibody discovery from single B cells.