Pore-forming Peptides and Protein Toxins
Sorozatcím: Cellular and Molecular Mechanisms of Toxic Action; 5;
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20% KEDVEZMÉNY?
- A kedvezmény csak az 'Értesítés a kedvenc témákról' hírlevelünk címzettjeinek rendeléseire érvényes.
- Kiadói listaár GBP 220.00
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111 342 Ft (106 040 Ft + 5% áfa)
Az ár azért becsült, mert a rendelés pillanatában nem lehet pontosan tudni, hogy a beérkezéskor milyen lesz a forint árfolyama az adott termék eredeti devizájához képest. Ha a forint romlana, kissé többet, ha javulna, kissé kevesebbet kell majd fizetnie.
- Kedvezmény(ek) 20% (cc. 22 268 Ft off)
- Kedvezményes ár 89 074 Ft (84 832 Ft + 5% áfa)
Iratkozzon fel most és részesüljön kedvezőbb árainkból!
Feliratkozom
111 342 Ft
Beszerezhetőség
Becsült beszerzési idő: A Prosperónál jelenleg nincsen raktáron, de a kiadónál igen. Beszerzés kb. 3-5 hét..
A Prosperónál jelenleg nincsen raktáron.
Why don't you give exact delivery time?
A beszerzés időigényét az eddigi tapasztalatokra alapozva adjuk meg. Azért becsült, mert a terméket külföldről hozzuk be, így a kiadó kiszolgálásának pillanatnyi gyorsaságától is függ. A megadottnál gyorsabb és lassabb szállítás is elképzelhető, de mindent megteszünk, hogy Ön a lehető leghamarabb jusson hozzá a termékhez.
A termék adatai:
- Kiadás sorszáma 1
- Kiadó CRC Press
- Megjelenés dátuma 2003. január 30.
- ISBN 9780415298520
- Kötéstípus Keménykötés
- Terjedelem348 oldal
- Méret 246x174 mm
- Súly 848 g
- Nyelv angol 0
Kategóriák
Rövid leírás:
Pore-forming proteins and peptides play a central role in bacterial pathogenesis, the immune response, venomous attack, and innate immunity. Pore-forming Peptides and Protein Toxins describes how natural and synthetic peptides and toxins form pores and ionic channels that cause cell membrane collapse and cell death. Written by researchers from around the world, it discusses such topics as the channel-forming properties of Helicobacter pylori and the role of amyloid peptide channels in the development of amyloid diseases. This text provides a multidisciplinary approach to understanding the basic principles and cellular mechanisms of the actions of toxins and their potential use as research tools.
Hosszú leírás:
Pore-forming proteins and peptides play a central role in bacterial pathogenesis, the immune response, defense from venomous attack, and innate immunity. These proteins attack and eliminate other organisms by punching an aqueous channel through their membranes, which disrupts appropriate cell function. The discovery of this cellular interaction has led to an abundance of scientific, medical, and commercial applications with unlimited potential.
Pore-forming Peptides and Protein Toxins describes how natural and synthetic peptides and toxins form pores and ionic channels that cause cell membrane collapse and cell death. Divided into two parts on pore-forming proteins and pore-forming peptides, each chapter reviews the normal physiological cellular structure and function, discusses the interference of toxins with this process, and considers the use of specific toxins in research. Written by researchers from around the world, the text includes such topics as the channel-forming properties of Helicobacter pylori and the role of amyloid peptide channels in the development of amyloid diseases.
This authoritative volume provides a multidisciplinary approach to understanding the basic principles and cellular mechanisms of the action of toxins and their potential use as research tools. It is an essential work for researchers and students in the fields of biochemistry, toxicology, biophysics, and pharmaceutical science.
Tartalomjegyzék:
PART 1 PORE-FORMING PROTEINS. Staphylococcal Bicomponent Leucotoxins, Mechanisms of Action, Impact on Cells and Contribution to Virulence. The Formulation of Ion-permeable Channels by RTX-toxins in Lipid Bilayer Membranes: Basis for Their Biological Activity. Properties of the Monomeric and the Pentameric Pseudomonas Cytotoxin. Helicobacter pylori Vacuolating Toxin VacA: Channel-forming Properties and Cell Intoxication. Delta-endotoxin Mode of Action. Functional Studies of Helix a-5 Region from Bacillus Thuringiensis Cryl1Ab d-endotoxin. Colicin Channels and Protein Translocation: Parallels with Diphtheria Toxin. Actinoporins, Pore-forming Toxins of Sea Anemones (Actiniaria). PART 2 PORE-FORMING PEPTIDES. Structural and Change Requirements for Antimicrobial Peptide Insertion into Biological and Model Membranes. Pardaxins - Pore-forming Neurotoxins as Pharmaceutical Tools in Dissecting Neurotransmitter Exocytosis and Neurotoxicity. Cecropin-melittin Hybrid Peptides as Versatile Templates in the Development of Membrane-active Antibiotic Agents. The Syringomycins: Lipodepsipeptide Pore Formers from Plant Bacterium Pseudomonas syringae. Molecular Mechanisms of Action of Syringopeptins, Antifungal Peptides from Pseudomonas syringae pv. syringae. The Role of Amyloid Peptide Channels in Amyloid Disease.
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