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    Novel Inhibitors of Leukotrienes
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        92 475 Ft (88 072 Ft + 5% áfa)
      • Kedvezmény(ek) 20% (cc. 18 495 Ft off)
      • Discounted price 73 980 Ft (70 458 Ft + 5% áfa)

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    Rövid leírás:

    Many new antileukotriene drugs are now marketed as antiasthma drugs and
    represent the first new drugs in this field since the 1970s. This book
    covers the steps that have led to the discovery and development of these
    new drugs and offers detailed descriptions of their clinical
    applications.
    The volume takes a new approach in presenting information of particular
    interest to both scientists and clinicians...

    Több

    Hosszú leírás:

    Many new antileukotriene drugs are now marketed as antiasthma drugs and
    represent the first new drugs in this field since the 1970s. This book
    covers the steps that have led to the discovery and development of these
    new drugs and offers detailed descriptions of their clinical
    applications. The review chapters on the main aspects of basic and
    applied leukotriene research are written by leading specialists in the
    field, and the volume takes a new approach in presenting information of
    particular interest to both scientists and clinicians in the fields of
    asthma, inflammation and allergic diseases.

    Több

    Tartalomjegyzék:

    5-Lipoxygenase.- LTC4 synthase: A key enzyme in cysteinyl leukotriene formation.- Leukotriene A4 hydrolase: A key enzyme in chemotactic leukotriene formation.- Metabolism of leukotrienes and formation of new leukotriene structures.- Receptors for cysteinyl-leukotrienes: Targets for new drugs.- Targeted disruption of 5-lipoxygenase.- Transcellular biosynthesis of leukotrienes: A unique mode of cell communication.- Physiological and pathophysiological activities of leukotrienes.- Entry rate and metabolic handling of LTC4 in the human circulation.- Genetic polymorphisms of 5-LO.- Leukotrienes and aspirin-intolerant asthma.- Leukotrienes in nocturnal asthma.- Leukotrienes and allergic asthma.- Inhibitors of leukotrienes: An overview.- The development of zafirlukast (Accolate?) and the Zeneca series of peptidyl-leukotriene receptor antagonists.- The development of zileuton (ZYFLO?) and the N-hydroxyurea class of 5-lipoxygenase inhibitors.- The development of BAY X 1005 and the Bayer series of leukotriene biosynthesis inhibitors.- The development of iralukast: A member of the Novartis series of cysteinyl leukotriene antagonists.- LTB4 receptor antagonists.- SmithKline Beecham pharmaceuticals? cysteinyl leukotriene receptor antagonists: Pranlukast (SB 205312; Ono-1078; Onon), Pobilukast (SK&F 104353) and SK&F 106203.

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    Készleten
    Novel Inhibitors of Leukotrienes

    Novel Inhibitors of Leukotrienes

    Folco, Giancarlo; Samuelsson, Bengt; Murphy, Robert C.; (ed.)

    92 475 Ft

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