Nanotoxicology

Toxicity Evaluation of Nanomedicine Applications
 
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Kiadó: CRC Press
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A kedvezmény érvényes eddig: 2024. június 30.
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  példányt

 
Rövid leírás:

This book delivers comprehensive coverage in the field with fundamental understanding, serving as a platform to convey essential concepts of nanotoxicology and how these concepts can be employed to develop advanced nanomaterials for a range of biomedical applications.

Hosszú leírás:

The field of nanomedicine has risen quickly due to the increasing number of designer-made nanomaterials. These nanomaterials have the potential to manage diseases and change the way medicine is currently studied. However, the increased practice of using nanomaterials has shed light on how many concepts of nanomedicine and nanotoxicity have been overlooked. Nanotoxicology: Toxicity Evaluation of Nanomedicine Applications addresses the existing gaps between nanomedicine and nanotoxicity. This book also brings together up-to-date knowledge on advances toward safe-by-design nanomaterials and existing toxicity challenges.



This book delivers a comprehensive coverage in the field with fundamental understanding, serving as a platform to convey essential concepts of nanotoxicology and how these concepts can be employed to develop advanced nanomaterials for a range of biomedical applications. This book is an effort to answer some of the thoughtful nanotoxicological complications and their auspicious probable solutions with new approaches and careful toxicity assessment.



Key Features:




  • Reveals novel nanoscale approaches, toxicity assessment, and biomedical applications



  • Includes importance of nanotoxicity concepts in developing smart nanomaterials



  • Highlights unique contributions and "A to Z" aspects on the state-of-the-art from global leaders



  • Offers a complete package to learn fundamentals with recommendations on nanomaterials toxicity and safe-by-design nanomedicines



Nanotoxicology: Toxicity Evaluation of Nanomedicine Applications illuminates the high potential of many innovative nanomaterials, ultimately demonstrating them to be promising substitutes for available therapies that can be effectively used in fighting a myriad of biomedical complications. Further, this book reports legal, ethical, safety, and regulatory issues associated with nanomaterials, which have often been neglected, if not overlooked in literature and limiting clinical translation at nanoscale level. It will equip readers with cutting-edge knowledge of promising developments in nanomedicine and nanotoxicology, along with potential future prospects.



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Tartalomjegyzék:

Chapter 1 Nanomaterials: Types of Nanomaterials and Their


Fundamental Physicochemical Properties....................................... 1


A. Shubha, S. R. Manohara, and S. S. Subhranshu


Chapter 2 Innovations in Nanotechnology for Biomedical Sensing,


Imaging, Drug Delivery, and Therapy........................................... 21


Anine Crous and Heidi Abrahamse


Chapter 3 Nanomaterials for Drug Delivery.................................................. 43


Shailja Jain, Srividya Gorantla, and Gautam Singhvi


Chapter 4 PLGA-Based Nanoparticulate Systems: New Trends in


Nanomedicine................................................................................ 73


Devendra Jain, Abhijeet Singh, Bjorn John Stephen,


Suman Sanadhya, Hemant Kumar Daima,


Harishkumar Madhyastha, and Radha Madhyastha


Chapter 5 Employing New Targeted Nanoencapsulation for


Alzheimer?s Disease Treatment: A Change for the Better?........... 97


Arti Devi and Zaved Ahmed Khan


Chapter 6 Nanomaterials-Assisted Elicitation of


Pharmaceutically Important Secondary Metabolites from


In Vitro Plant Cell Cultures...........................................................117


Sekhar Tiwari, Sachin Kumar Verma, Abhishek Bhargava,


Anusha Ebenezer Alpheus, Rasanpreet Kaur,


Rajesh Sharma, and Neeraj Khare


Chapter 7 Impact of Nanomaterials on Health and Environment................ 133


Faisal Ali, Kanwal Akhtar, Ahmed Nawaz, M. Munir Sajid,


Naveed Akhtar Shad, Muhammad Abdul Qayyum, and Yasir Javed


Chapter 8 Consequences of Nanomaterials on Human


Health and Ecosystem.................................................................. 157


Priyanka Kumari, Richa Seth, and Abha Meena


Chapter 9 Conceptual Understanding of the Mechanisms of


Nanotoxicity and Safety of Nanomedicines................................. 201


Rotimi Damilare, Maimako Rotdelmwa, Ashonibare


Victory, Ogunnupebi Temitope, and Adeyemi Oluyomi Stephen


Chapter 10 Insights into the Mechanisms of Nanotoxicity and


Evaluation of Nanomaterials........................................................ 225


Vinod Kumar Yata


Chapter 11 Sensors to Monitor and Evaluate the Toxicity of


Nanomedicine Applications......................................................... 245


Bambang Kuswandi


Chapter 12 Systems Approaches for Toxicological


Assessment of Nanomaterials...................................................... 277


Hasmik Yepiskoposyan, Marja Talikka,


Vincenzo Belcastro, Nikolai V. Ivanov, Diego Marescotti,


Manuel C. Peitsch, and Julia Hoeng


Chapter 13 Measurement of Oxygen Consumption Rate Based on


Fluorescence Intensity and Lifetime as a Strategy to Assess


Nanotoxicity................................................................................. 303


T. Sushma, Hemant Kumar Daima, D. R. Ramesh Babu,


S. Amutha, and Sangly P. Srinivas


Chapter 14 Current Knowledge on Toxicity of Nanomaterials:


Toxicity Assessment and Impact.................................................. 339


Bhaskar Das, Mayuri Chabukdhara, Sanjukta Patra, and


Manashjit Gogoi


Chapter 15 The Role of Nanotechnology in the Management of


Water Toxicity.............................................................................. 377


Vinod Kumar Yata


Chapter 16 Challenges in the Assessment of Nanotoxicity,


Recommendations, and Safe-by-Design Nanomedicines to


Counter Toxicological Problems.................................................. 393


G. V. S. Subbaroy Sarma, Manoj Kumar Enamala,


Maria P. Nikolova, Murthy Chavali, and


Sudhakar Reddy Pamanji


Chapter 17 Current Guidelines and Regulatory Challenges, Insight into


the Legal, Societal, and Ethical Issues of Nanomaterials............ 445


Harjeet Nath, S. S. Subhranshu, and S. R. Manohara