Rövid leírás:

This book provides the background necessary to understand, interpret, and apply sequencing information to real world problems. Replication of genetic material, the structure of DNA, typing methods and forensic applications are all discussed in this useful primer.

Hosszú leírás:

Sequencing genetic material is now common practice. The general population have become consumers of this information but without an understanding of the biological processes that render sequencing data useful. The interpretation of genetic sequence depends on an appreciation of the basics of genetics and the limits of such data. This book provides the background necessary to understand, interpret, and apply sequencing information to real- world problems. Replication of genetic material, the structure of DNA, typing methods, and forensic applications are all discussed in this useful primer.

Key Features

? Provides self-learning about DNA fingerprinting.

? Includes sections on how to analyze and interpret DNA fingerprinting.

? Covers legal and medicolegal issues and case analyses.

? Teaches novice legal community about DNA fingerprints.

? Summarizes for a general audience the role of ancestry, DNA, and what that means.

Tartalomjegyzék:

1. Forward






2. Introduction








3. CHAPTER 1: The Cell








4. CHAPTER 2: How do cells divide and why is it important to know the process?








5. CHAPTER 3: Structure of DNA and why we use DNA in Forensic Science.








6. CHAPTER 4: Capillary Gel Electrophoresis for analysis of DNA in Crime Labs








7. CHAPTER 5: Sex Determination by STR








8. CHAPTER 6: The Combined DNA Index System (CODIS)








9. CHAPTER 7: How STRs are analyzed in a Forensic Laboratory








10. CHAPTER 8: Complexities of Sex Determination








11. CHAPTER 9: Y-STR and Paternal Ancestry








12. CHAPTER 10: Mitochondrial STRs








13. CHAPTER 11: Forensic Serology








14. CHAPTER 12: How to extract DNA from a biological sample








15. CHAPTER 13: A guide to understanding the value of DNA results: A short discussion on Probability and Statistical Calculations.








16. CHAPTER 14: What are autosomal dominant, recessive, and X-linked dominant and recessive traits?