Exposure Toxicology in Caenorhabditis elegans

Exposure Toxicology in Caenorhabditis elegans

 
Kiadás sorszáma: 1st ed. 2020
Kiadó: Springer
Megjelenés dátuma:
Kötetek száma: 1 pieces, Book
 
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A termék adatai:

ISBN13:9789811561283
ISBN10:9811561281
Kötéstípus:Keménykötés
Terjedelem:682 oldal
Méret:235x155 mm
Súly:1341 g
Nyelv:angol
Illusztrációk: 144 Illustrations, black & white; 303 Illustrations, color; 302 Tables, color
241
Témakör:
Rövid leírás:

This book focuses on exposure toxicology in C. elegans. The nematode Caenorhabditis elegans is sensitive to various environmental toxicants and stresses, and has proven to be an important animal model in both molecular and target-organ toxicology. As a result, over the past 30 years, there has been extensive research on the exposure to environmental toxicants or stresses in nematodes. Based on the available data, the book offers an introduction to the exposure system established in nematodes, discussing various aspects of endpoints that can potentially be used to assess the toxicity of environmental toxicants or stresses. Also exploring various factors affecting toxicity induction, and exposure to environmental toxicants and stresses, it allows readers to gain a systematic understanding of exposure toxicology in C. elegans. 

Hosszú leírás:

This book focuses on exposure toxicology in C. elegans. The nematode Caenorhabditis elegans is sensitive to various environmental toxicants and stresses, and has proven to be an important animal model in both molecular and target-organ toxicology. As a result, over the past 30 years, there has been extensive research on the exposure to environmental toxicants or stresses in nematodes. Based on the available data, the book offers an introduction to the exposure system established in nematodes, discussing various aspects of endpoints that can potentially be used to assess the toxicity of environmental toxicants or stresses. Also exploring various factors affecting toxicity induction, and exposure to environmental toxicants and stresses, it allows readers to gain a systematic understanding of exposure toxicology in C. elegans. 

Tartalomjegyzék:

1. Exposure Durations of Environmental Stresses or Toxicants



2. Exposure Stages of Environmental Stresses or Toxicants



3. Complex Exposures to Environmental Toxicants or Stresses



 4. Transgenerational Toxicity of Environmental Toxicants or Stresses



 5. Exposure Routes of Environmental Toxicants



6. Basic Endpoints for Toxicity Assessment of Environmental Toxicants or Stresses



 7. Endpoints for Assessing the Toxicity on Primary Targeted Organs



 8.  Endpoints for Assessing the Toxicity on Secondary Targeted Organs



 9. Endpoints for Assessing the Toxicity on Biochemical Processes



 10. Endpoints for Assessing the Genotoxicity and the Genetic Toxicity



 11. Role of Exposure Dose in Toxicity Induction of Environmental Toxicants or Stresses



 12. Role of Environmental Factors in Toxicity Induction of Environmental Toxicants or Stresses



 13. Effects of Environmental Sample Forms on Toxicity Induction



 14. Roles of Physicochemical Properties of Toxicants in Toxicity Induction



 15. Roles of Environmental Media and Chemical Transformations of Environmental Toxicants in Toxicity Induction



16. Bioavailability, Enrichment, and Translocation of Environmental Toxicants



17. Susceptibility to Toxicants or Stresses Induced by Genetic Mutations



18. Contributors to Amplify the Toxicity of Toxicants or Stresses



 19. Exposure to Certain Environmental Stresses



20. High-Throughput Toxicity Assessment



21. Toxicity Assessment under the Pathological Conditions