Rövid leírás:

Many new drugs on the market are chiral compounds, that is, they can exist in two non-superimposable mirror-image forms. Asymmetric catalysis encompasses a large variety of processes for obtaining such compounds.

Hosszú leírás:

Many new drugs on the market are chiral compounds, that is, they can exist in two non-superimposable mirror-image forms. Asymmetric catalysis encompasses a large variety of processes for obtaining such compounds. The performance of the catalyst in those processes largely depends on the ligand that makes up the catalyst. This book describes the most relevant ligand libraries for some key processes, including an overview of the state of art and the key mechanistic aspects that favor a high catalytic performance.

Key Features:

• The book presents historical content from the time of discovery for each family of ligands.


• Provides a description of the synthetic route and the ligand library's application in various catalytic asymmetric reactions


• Suitable as supplementary reading for courses targeting the design, synthesis and application of chiral catalysts, asymmetric catalysis and sustainable production


• Edited by a distinguished scientist in the field, the book has a diverse audience including research groups in homogeneous catalysis, particularly asymmetric transformations

Tartalomjegyzék:

Contents

Preface......................................................................................................................vii

Editor.........................................................................................................................ix

List of Contributors....................................................................................................xi

Abbreviations and Acronyms................................................................................. xiii

Chapter 1 Chiral Bidentate Heterodonor P-Oxazoline Ligands ...........................1

Chapter 2 Chiral Bidentate Heterodonor P-N-Other-Ligands............................. 33

Chapter 3 Chiral Bidentate Heterodonor P,S/O Ligands..................................... 81

Chapter 4 Chiral Bidentate Heterodonor P-P? ligands....................................... 109

Chapter 5 Chiral Tridentate-Based Ligands...................................................... 167

Chapter 6 Chiral N-Heterocyclic Carbene-Based Ligands................................ 195

Chapter 7 Chiral Monophosphorus Ligands...................................................... 233

Chapter 8 Solvent-Oriented Ligand and Catalyst Design in Asymmetric

Catalysis ? Principles and Limits ..................................................... 261

Index....................................................................................................................... 315