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    Towards a Theory of Development

    Towards a Theory of Development by Minelli, Alessandro; Pradeu, Thomas;

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    Product details:

    • Publisher OUP Oxford
    • Date of Publication 1 May 2014

    • ISBN 9780199671434
    • Binding Paperback
    • No. of pages304 pages
    • Size 246x190x16 mm
    • Weight 662 g
    • Language English
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    Short description:

    This volume explores the foundations of ontogeny by asking how the development of living things should be understood. It explores key concepts of developmental biology, asks whether general principles of development can be discovered, and what the role of models and theories is in developmental biology.

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    Long description:

    Is it possible to explain and predict the development of living things? What is development? Articulate answers to these seemingly innocuous questions are far from straightforward. To date, no systematic, targeted effort has been made to construct a unifying theory of development. This novel work offers a unique exploration of the foundations of ontogeny by asking how the development of living things should be understood. It explores the key concepts of developmental biology, asks whether general principles of development can be discovered, and examines the role of models and theories.

    The two editors (one a biologist with long interest in the theoretical aspects of his discipline, the other a philosopher of science who has mainly worked on biological systems) have assembled a team of leading contributors who are representative of the scientific and philosophical community within which a diversity of thoughts are growing, and out of which a theory of development may eventually emerge. They analyse a wealth of approaches to concepts, models and theories of development, such as gene regulatory networks, accounts based on systems biology and on physics of soft matter, the different articulations of evolution and development, symbiont-induced development, as well as the widely discussed concepts of positional information and morphogenetic field, the idea of a 'programme' of development and its critiques, and the long-standing opposition between preformationist and epigenetic conceptions of development.

    Towards a Theory of Development is primarily aimed at students and researchers in the fields of 'evo-devo', developmental biology, theoretical biology, systems biology, biophysics, and the philosophy of science.

    [a] splendid book ... The complementary perspectives of the editors helped to bring together an exceptional team of contributors that includes both biologists and philosophers. ... this book should be required reading for philosophers and biologists interested in development or evolutionary developmental biology

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    Table of Contents:

    Theories of Development in Biology - Problems and Perspectives
    Regenerating Theories in Developmental Biology
    The Erotetic Organization of Developmental Biology
    On the Concept of Mechanism in Development
    The Epistemological Resilience of the Concept of Morphogenetic Field
    Physico-genetics of Morphogenesis: The Hybrid Nature of Developmental Mechanisms
    The Landscape Metaphor in Development
    Formalizing Theories of Development: A Fugue on the Orderliness of Change
    General Theories of Evolution and Inheritance, but not Development?
    Cell Differentiation Is a Stochastic Process Subjected to Natural Selection
    From Genes to Gene Regulatory Networks: The Progressive Historical Construction of a Genetic Theory of Development and Evolution
    Reproduction and Scaffolded Developmental Processes: An Integrated Evolutionary Perspective
    Comparison of Animal and Plant Development: A Right Track to Establish a Theory of Development?
    Toward a Theory of Development Through a Theory of Developmental Evolution
    Developmental Disparity
    Identifying Some Theories in Developmental Biology. The Case of the Cancer Stem Cell Theory
    Animal Development in a Microbial World
    Foreword: a biologist's view by Brian K. Hall
    Foreword: a philosopher's view by Richard M. Burian

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