The SV40 Replicon Model for Analysis of Anticancer Drugs
Series: Biotechnology Intelligence Unit;
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45 813 Ft
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Product details:
- Publisher Academic Press
- Date of Publication 23 May 1996
- ISBN 9780126536300
- Binding Hardback
- No. of pages200 pages
- Size 257x182 mm
- Weight 730 g
- Language English 0
Categories
Long description:
This book provides the most up-to-date review of the simian virus 40 (SV40) minichromosome as a model for the mammalian chromosome in studies of DNA replication. It focuses on disruption of DNA replication by anticancer drugs and DNA-damaging agents. There is a strong emphasis on the unique advantages of SV40 as an experimental system for the analysis of these classes of anticancer drug mechanisms. The new high-resolution gel electrophoresis methods for the analysis of SV40 DNA replication are covered in detail to aid readers in designing and interpreting similar experiments.
MoreTable of Contents:
R.M. Snapka, Papovavirus Models for Mammalian Replicons.R.M. Snapka, Analysis of SV40 DNA Replication Intermediates.R.M. Snapka, Catastrophic Failure of DNA Replication Forks: Structural and RecombinationalPathways.R.M. Snapka and E.F. Yamasaki, Topoisomerase II and the Termination of DNA Replication.R.M. Snapka, DNA Damaging Agents.R.M. Snapka, C.A. Ferrar, N.-J. Sun, and J.M. Cassady, Drug Discovery and Evaluation with SV40.L.H. Malkas, Simian Virus 40 (SV40) in Vitro DNA Replication: A Potential Model for Studying Anticancer Drug Action.R.M. Snapka and P.A. Permana, SV40 Circular Oligomer Series: Normal and Abnormal DNA Replication.Subject Index.
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