Long description:

The Enzymes, Volume 54 highlights new advances in enzymes, with new chapters on a variety of topics, including the History of The Enzymes, Impact of The Enzymes in chronicling biochemical processes and pathways, Metabolism and Catalysis, Mitochondrial ATP synthase, The respiratory chain, A century of mitochondrial research, Five decades of metalloenzymology, Mechanisms of catalysis, Mitochondrial fatty acid synthesis and associated processes, Signaling, MAPK cascades: Origins, mechanisms and current status, Sphingolipids: From structural components to signaling hubs, Protein Homeostasis and Hydrolysis, Mitochondrial AAA+ proteases, Hsp70 and JDP proteins: structure-function perspective on molecular chaperone activity.

Other sections cover DNA Replication and Repair, Structure-function studies of DNA replication proteins, and Helicases required for nucleotide excision repair.

Table of Contents:

I. Introduction
1. History of The Enzymes
Fuyuhiko Tamanoi,
2. Impact of The Enzymes in chronicling biochemical processes and pathways
Laurie S. Kaguni

II. Metabolism and Catalysis
3. Mitochondrial ATP synthase
John Walker
4. The respiratory chain
M?rten Wikström
5. A century of mitochondrial research
Howard Jacobs
6. Five decades of metalloenzymology
Robert P. Hausinger
7. Mechanisms of catalysis
Kenneth Allen Johnson
8. Mitochondrial fatty acid synthesis and associated processes
Alexander Kastaniotis

III. Signaling
9. MAPK cascades: Origins, mechanisms and current status
Jeremy Thorner
10. Sphingolipids: From structural components to signaling hubs
Johnny Stiban and Saurav Majumder

IV. Protein Homeostasis and Hydrolysis
11. Mitochondrial AAA+ proteases
Yuichi Matsushima
12. Hsp70 and JDP proteins: structure-function perspective on molecular chaperone activity
Szymon Ciesielski

V. DNA Replication and Repair
13. Structure-function studies of DNA replication proteins
Borja Ibarra
14. Helicases required for nucleotide excision repair
Li Fan