Proteins: A Very Short Introduction
Series: Very Short Introductions;
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Product details:
- Publisher OUP Oxford
- Date of Publication 1 February 2019
- ISBN 9780198807124
- Binding Paperback
- No. of pages160 pages
- Size 174x111 mm
- Language English
- Illustrations 27 black and white images 0
Categories
Short description:
Proteins form an essential part of all living creatures. Introducing the chemistry behind our biology, this book describes the 4-billion-year evolutionary history of proteins, discusses their structure, and explores what happens when proteins go wrong. Looking forward, it includes recent discoveries of the therepeutic potential of proteins.
MoreLong description:
Proteins form an essential part of all living creatures. Our muscles, our organs, our enzymes, and our antibodies are all composed structurally of these large molecules. TThese foundational units of life consist of a complex biological polymer, or more correctly co-polymer (composed of more than one monomer) - a macromolecule generated from long chains of at least 22 different amino acids. The different options available from 22 different monomers at each position
in a protein chain allows the generation of astronomical numbers of different proteins and it is within this, so-called, protein hyperspace, that evolution works.
In this Very Short Introduction Brian Henderson introduces the chemistry at work behind our biology. Considering the 4 billion year evolutionary history of proteins, he discusses their structure, and the carefully balanced interplay between protein synthesis (the process where new proteins are generated by biological cells) and degradation (the death of protein molecules). Henderson also considers what can happen when proteins go wrong, exploring the wide variety of human pathological
states which can result from protein unfolding or misfolding, including a range of genetic diseases. Looking forward, he shows how proteins have recently been found to have therapeutic potential, and touches on the fast growing use of therapeutic antibodies to treat human disease.
ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
Table of Contents:
Preface
Chicken and egg: a 4 billion year history of proteins
Protein building blocks
Molecular machines and protein synthesis
Protein structure: folding, folding, folding
Proteins meet -Omics
Enzymes: protein time transformers
Communicating proteins
Antibodies: very unusual proteins
Protein machines
Proteins giveth and proteins taketh away
Further reading
Index
