Protein Dynamics
Experimental and Computational Approaches
Series: Foundations and Frontiers in Enzymology;
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63 663 Ft
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Product details:
- Publisher Elsevier Science
- Date of Publication 1 September 2026
- ISBN 9780443300424
- Binding Paperback
- No. of pages442 pages
- Size 235x191 mm
- Weight 450 g
- Language English 0
Categories
Long description:
Protein Dynamics: Experimental and Computational Approaches investigates protein biology from a biophysical standpoint. The book covers a wide range of topics, including functional protein dynamics, intrinsically disordered proteins, protein folding, misfolding and aggregation, and membrane protein-protein communication. Protein allosteric conformational changes caused by drug binding and disease-associated mutations are also featured, alongside protein dynamics in the context of computer-based drug design. Biophysical techniques for investigating protein structure-dynamics-function relationships across these topics are explored, considering the latest experimental and computational approaches in the field. This book is an ideal reference for researchers in working in biophysics, biochemistry, and related areas.
MoreTable of Contents:
1. Introduction
2. Functional protein dynamics
3. Protein-protein communication in membrane protein organization and cell signaling
4. Intrinsically disordered proteins
5. Role of entropy in protein folding
6. Functional water molecules and role of ions in protein function
7. Computing transition states in enzyme reactions
8. G Protein Receptor Signaling
9. Protonation-coupled protein dynamics studied with graph algorithms
10. Membrane transporters
11. Lipids and lipid-protein dynamics in membrane protein function
12. Protein misfolding and aggregation
13. Proteins of extremophiles
14. Protein allosteric conformational changes caused by drug binding and disease-associated mutations
15. Computer-based drug design
16. Amyloid precursor protein in Alzheimer's disease