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  • Progress in Molecular Biology and Translational Science: Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part A

    Progress in Molecular Biology and Translational Science

    Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part A

    Series: Progress in Molecular Biology and Translational Science; 162;

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    Product details:

    • Publisher Elsevier Science
    • Date of Publication 23 March 2019

    • ISBN 9780128177389
    • Binding Hardback
    • No. of pages418 pages
    • Size 229x152 mm
    • Weight 840 g
    • Language English
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    Long description:

    Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part A, Volume 162 in the Progress in Molecular Biology and Translational Science series provides informative monographs on a variety of research topics related to Glycans and glycosaminoglycans as clinical biomarkers and therapeutics. Topics in this update include Glycan-based Biomarkers for Diagnosis of Cancers and Other Diseases: Past, Present and Future, Desialylation in Diseases and its Application in Diagnostic and Therapeutic Development, Proteoglycans as Miscommunication Biomarkers for Cancer Diagnosis, Fucosylation in Cancer Biology and Its Clinical Applications, Retrospective Analysis of Glycan-Related Biomarkers Based on Clinical Laboratory Data in Two Medical Centers, and many related topics.

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    Table of Contents:

    1. Glycan-based biomarkers for diagnosis of cancers and other diseases: Past, present, and future
    Minghui Hu, Ying Lan, Alexander Lu, Xuexiao Ma and Lijuan Zhang
    2. Desialylation in physiological and pathological processes: New target for diagnostic and therapeutic development
    Mohui Wei and Peng George Wang
    3. Proteoglycans as miscommunication biomarkers for cancer diagnosis
    Lingling Xu, Limin Tang and Lijuan Zhang
    4. Fucosylation in cancer biology and its clinical applications
    Ming Shan, Dandan Yang, Huaiqian Dou and Lijuan Zhang
    5. The sensitivity and specificity of serum glycan-based biomarkers for cancer detection
    Yang Tang, Yidi Cui, Shufeng Zhang and Lijuan Zhang
    6. Retrospective analysis of glycan-related biomarkers based on clinical laboratory data in two medical centers during the past six years
    Meng Zhang, Huaiqian Dou, Dandan Yang, Ming Shan, Xiulian Li, Cui Hao, Yiran Zhang, Pengjiao Zeng, Yanli He, Yong Liu, Jing Fu, Wei Wang, Minghui Hu, Hui Li, Qingwu Tian, Shuhe Lei and Lijuan Zhang
    7. Serum SCCA levels in patients suffering cancers or other diseases
    Dandan Yang, Jun Wang and Lijuan Zhang
    8. Increased serum CA724 levels in patients suffering gout vs cancers
    Yiran Zhang, Meng Zhang, Xueshan Bai, Changgui Li and Lijuan Zhang
    9. Serum CA50 levels in patients with cancers and other diseases
    Ming Shan, Qingwu Tian and Lijuan Zhang
    10. Serum AFP levels in patients suffering from 47 different types of cancers and noncancer diseases
    Yanli He, Haijun Lu and Lijuan Zhang
    11. Serum CEA levels in 49 different types of cancer and noncancer diseases
    Cui Hao, Guoqing Zhang and Lijuan Zhang
    12. CA242 as a biomarker for pancreatic cancer and other diseases
    Huaiqian Dou, Guirong Sun, and Lijuan Zhang
    13. Serum CA125 levels are decreased in rectal cancer but increased in fibrosis-associated diseases and in most types of cancers
    Meng Zhang, Yiran Zhang, Jing Fu and Lijuan Zhang
    14. Serum CA199 levels are significantly increased in patients suffering from liver, lung, and other diseases
    Pengjiao Zeng, Hui Li, Yulong Chen, Haitao Pei and Lijuan Zhang
    15. Serum CA153 as biomarker for cancer and non-cancer diseases
    Xiulian Li, Yan Xu and Lijuan Zhang
    16. Fasting blood glucose levels in patients with different types of diseases
    Qinghua Zhang, Gang Zhao, Nailong Yang and Lijuan Zhang
    17. HbA1c: High in acute cerebral infarction and low in brain trauma
    Zhifeng Jiang, Jigang Wang, Peng Zhao, Lijuan Zhang and Yunliang Guo
    18. Glycated albumin level is significantly decreased in patients suffering nephrotic syndrome
    Zhe Wang, Guangqun Xing, Lijuan Zhang
    19. Glycated serum proteins: High in pancreatic cancer and low in preeclampsia
    Xueling Wang, Rui Zhang, Lijuan Zhang and Zibin Tian
    20. The serum SA levels are significantly increased in sepsis but decreased in cirrhosis
    Xiaodan Huang, Qin Yao, Lijuan Zhang and Zibin Tian
    21. Serum ?-L-fucosidase activities are significantly increased in patients with preeclampsia
    Meng Zhang, Lin Wang, Haiping Zhang, Juan Cong and Lijuan Zhang
    22. Glucuronidated bilirubin: Significantly increased in hepatic encephalopathy
    Limin Tang, Meng Zhang, Xiulian Li and Lijuan Zhang
    23. Serum PSA levels in patients with prostate cancer and other 33 different types of diseases
    Yanyun Gao, Meng Zhang, Xiulian Li, Pengjiao Zeng, Peitao Wang and Lijuan Zhang

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