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15 760 Ft
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Product details:
- Publisher OUP Oxford
- Date of Publication 20 July 1995
- ISBN 9780198558248
- Binding Paperback
- No. of pages98 pages
- Size 245x188x6 mm
- Weight 206 g
- Language English
- Illustrations chemical structures 0
Categories
Short description:
Process development bridges the gap between the laboratory synthesis of an organic compound and its industrial manufacture on a large scale. This book uses real examples to show the range of problems which may be encountered in scaling up chemical syntheses and the ways in which they may be overcome.
MoreLong description:
Process development bridges the gap between the laboratory synthesis of an organic compound and its industrial manufacture on a large scale. In this concise text the authors use real examples to show the problems which may be encountered in scaling up chemical syntheses and the ways in which these problems may be overcome. The major part of the book is devoted to genuine case histories from ICI/Zeneca Pharmaceuticals. Through a range of carefully chosen examples, the book explains how it is possible to synthesise multi-kilogram quantities of a new organic compound which have been made in the laboratory only on the milligram scale. A wide range of aliphatic, aromatic, and heterocyclic compounds is covered. The book will be of particular value to research chemists who are involved in the development phase of novel compounds and to advanced undergraduate and postgraduate students interested in the fine chemicals industry.
excellent..volume
Table of Contents:
Introduction
Scale up issues
Environmental and regulatory issyes
Fun with cephalosporins
Thromboxane antagonists
Homochiral thrombozane antagonists
H2 blockers
Development of a manufacturing route for cloprostenol sodium
Synthesis of a potentially anti-obesity agent
Reagents for large scale operation
