Long description:

Phytopharmaceuticals and Herbal Drugs: Prospects and Safety Issues in the Delivery of Natural Products explores the delivery aspects of plant-based drugs, providing insights into formulation constraints associated with plant-based drugs, the development of novel delivery systems based on polymers or lipids, and how combining natural products with technological advancements in drug delivery is making large strides. Some of the best-selling drugs for the treatment of diseases like cancer, ulcers and malaria are either natural products or their derivatives, all of which are covered in this comprehensive resource.

This book will be useful to researchers working in plant-derived medicines and the development of their delivery systems, including sections on their derivatives and analogs that represent over 50% of all drugs in clinical use. Active ingredients originated from plant resources generally exhibit compromised desired effects limited by issues such as stability, solubility, molecular size, bioavailability and toxicity.

Table of Contents:

Section I. Prospects of Plant Based Therapeutics
1. Plant based therapeutics: Current status and future perspectives
2. Worldwide health scenario from the perspective of herbal medicine research

Section II. Challenges and Delivery Aspects of Phytomedicines and Bioactives
3. Challenges in delivery of plant actives
4. Lipid based particulate systems for delivery of plant actives and extracts: Extraction, prospective carriers and safety issues
5. Phyto-complexed systems as versatile tool for delivery of plant-based drugs
6. Impact of nanotechnology on herbal bioactives: An overview
7. Application of nanomedicine for efficient delivery of herbal bioactives
8. Nanophytomedicine: Nanotechnology for herbal product development and value addition

Section III. Safety Considerations, Regulatory and Commercial Aspects
9. Safety considerations in designing phytopharmaceuticals
10. Herbal drug interactions and effects on Phytopharmaceuticals
11. Clinical, ethical and regulatory issues of botanicals
12. Commercial aspect and market potential of phytoactive products

Section IV. Application Aspects of Phytopharmaceuticals
13. Interactions between radiopharmaceutical products and herbal medicines
14. Use of microfluidic organ-on-a-chip systems for screening and development of phytopharmaceuticals and herbal drugs
15. New and revisited approaches on the transdermal delivery of polyphenols-loaded nanoparticles for melanoma prevention and treatment
16. Novel drug delivery approaches for improving therapeutic applications of Berberine and Berberin-rich herbal preparations
17. Impact of phytomedicines and their novel delivery systems as an alternative for the treatment of neurodegenerative disorders
18. Role of phytopharmaceuticals in inflammatory disorders