Short description:

Physiological optical imaging is a group of emerging technologies that aim to provide healthcare practitioners and biomedical researchers with information about tissue physiology or pathophysiology using approaches different from traditional medical imaging (PET, ultrasound, MRI, X-ray, or CT scan).

Long description:

Physiological optical imaging is a group of emerging technologies that aim to provide healthcare practitioners and biomedical researchers with information about tissue physiology or pathophysiology using approaches different from traditional medical imaging (PET, ultrasound, MRI, X-ray, or CT scan).

This book provides a comprehensive review of this group of technologies, combining a current medical literature review with an overview of cutting-edge technologies, the physics behind them, and common features across different technologies. It presents technical and physiological considerations that impact the sensitivity and spatial resolution of each technology and practical ways to improve them. The book emphasises low-cost technologies, which can be implemented in point-of-care settings. It is illustrated primarily with examples from wound care and oncology, with additional examples from other medical fields, including ophthalmology and neuroimaging.

It can be used as a one-stop reference and practical guide for healthcare professionals, clinical researchers, and engineers working with emerging bioimaging technologies who are looking to utilise physiological optical imaging technologies in biomedical research or clinical practice.

Key Features:

• Provides a comprehensive review of current technologies.


• Written as a practical guide with physiological and design considerations and illustrations.


• Presents a 360-degree view on the topic: a combination of clinical information alongside a technological background.

Physiological Optical Imaging by Gennadi Saiko is a comprehensive exploration of optical imaging technologies aimed at providing healthcare providers and biomedical researchers with a detailed understanding of the physics, physiology, and engineering that makes this imaging possible. Saiko has a PhD in physics and a long history of applied bio optics to solve clinical problems. His background ensures that the content is both scientifically rigorous and practically relevant.

One notable aspect of the book is its emphasis on the importance of factors such as binning, spatial frequency sampling, and the distance to the target area in obtaining quantifiable and reproducible results in physiological imaging. These discussions are crucial for the proper design and clinical adoption of physiological imaging technologies.

In summary, "Physiological Optical Imaging" serves as a valuable resource for those interested in the advancements and applications of optical imaging in medicine. Saiko's expertise and comprehensive coverage of optical imaging make this book a significant contribution to the exciting field of bio photonics.?

- Bob Bartlett, MD, CPE, Chief Medical Officer, CutisCareUSA.com, March 2025

Table of Contents:

Chapter 1: What is Physiological Optical Imaging? Chapter 2: Resolution of Physiological Optical Imaging Techniques. Chapter 3: Contrast Ratio in Physiological Optical Imaging. Chapter 4: Sampling Depth in Physiological Optical Imaging. Chapter 5: Absorption-Based Physiological Optical Imaging Techniques. Chapter 6: Scattering-Based Physiological Optical Imaging Techniques. Chapter 7: Fluorescence-Based Physiological Optical Imaging Techniques. Chapter 8: Thermographic Physiological Optical Imaging Techniques. Chapter 9: Vibrational and Terahertz Techniques in Physiological Optical Imaging. Chapter 10: Other Approaches in Physiological Optical Imaging. Chapter 11: Endoscopic Physiological Optical Imaging. Chapter 12: Microscopic Physiological Optical Imaging. Chapter 13: Future Directions in Physiological Optical Imaging. Appendix A: Surface Tissues Morphology. Appendix B: Light Propagation in Tissues.