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  • Parsimony, Phylogeny, and Genomics

    Parsimony, Phylogeny, and Genomics by Albert, Victor A.;

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    Product details:

    • Edition number New ed
    • Publisher OUP Oxford
    • Date of Publication 16 March 2006

    • ISBN 9780199297306
    • Binding Paperback
    • No. of pages240 pages
    • Size 246x190x14 mm
    • Weight 450 g
    • Language English
    • Illustrations Numerous line drawings and tables
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    Short description:

    Parsimony analysis (cladistics) has long been one of the most widely used methods of phylogenetic inference in the fields of systematic and evolutionary biology. Moreover it has mathematical attributes that lend themselves for use with complex, genomic-scale data sets. This book demonstrates the potential that this powerful hierarchical data summarization method also has for both structural and functional comparative genomic research.

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    Long description:

    Parsimony analysis (cladistics) has long been one of the most widely used methods of phylogenetic inference in the fields of systematic and evolutionary biology. Moreover it has mathematical attributes that lend itself for use with complex, genomic-scale data sets. This book demonstrates the potential that this powerful hierarchical data summarization method also has for both structural and functional comparative genomic research.

    "Many readers might be wondering why a simple principle such as parsimony would be so useful in a technologically advanced area of study like genomics. The answer is found within the pages of this volume." The Quarterly Review of Biology, Volume 82, Rob DeSalle, American Museum of Natural History

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    Table of Contents:

    Preface
    Parsimony and phylogenetics in the genomic age
    The philosophy of parsimony analysis, including comparison with model-based approaches
    What is the rationale for 'Ockham's Razor' (a.k.a. parsimony) in phylogenetic inference?
    Parsimony and its presuppositions
    Parsimony, character analysis, and optimization of sequence characters
    The logic of the data matrix in phylogenetic analysis
    Alignment, dynamic homology, and optimization
    Parsimony and the problem of inapplicables in sequence data
    Computational limits of parsimony analysis: from historical aspects to competition with fast model-based approaches
    The limits of conventional cladistic analysis
    Parsimony and Bayesian phylogenetics
    Mathematical attributes of parsimony
    Maximum parsimony and the phylogenetic information in multi-state characters
    Parsimony and genomics
    Using phylogeny to understand genomic evolution
    Dollo parsimony and reconstruction of genome evolution
    References
    Index

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