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  • Osteoimmunology: Interactions of the Immune and Skeletal Systems

    Osteoimmunology by Lorenzo, Joseph; Horowitz, Mark; Choi, Yongwon; Takayanagi, Hiroshi;

    Interactions of the Immune and Skeletal Systems

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      • Publisher's listprice EUR 84.95
      • The price is estimated because at the time of ordering we do not know what conversion rates will apply to HUF / product currency when the book arrives. In case HUF is weaker, the price increases slightly, in case HUF is stronger, the price goes lower slightly.

        35 233 Ft (33 555 Ft + 5% VAT)
      • Discount 10% (cc. 3 523 Ft off)
      • Discounted price 31 709 Ft (30 200 Ft + 5% VAT)

    35 233 Ft

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    Out of print

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    Product details:

    • Publisher Elsevier Science
    • Date of Publication 24 September 2010

    • ISBN 9780123756701
    • Binding Hardback
    • No. of pages470 pages
    • Size 235x191 mm
    • Weight 1210 g
    • Language English
    • 0

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    Long description:

    Bone and the immune system are both complex tissues, which, respectively, regulate the skeleton and the body's responses to invading pathogens. Critical interactions between these two organ systems frequently occur, particularly in the development of immune cells in the bone marrow and for the function of bone cells in health and disease. This book provides a detailed overview of the many ways that bone and immune cells interact. The goal is to provide basic and clinical scientists with a better understanding of the role that the immune system and bone play in the development and function of each other so that advances in both fields will be facilitated. The focus of the book will be both on basic pathways and translational science, which will apply basic knowledge to clinical diseases. Chapter content will range from basic descriptions of the various cell systems and their development to the signals that cause them to interact during normal physiology and disease. This is a rapidly developing area that is of interest to a wide spectrum of researchers, students, and fellows in immunology, rheumatology, hematology, and bone biology--all of whom need to develop a more complete understanding of their previously separate disciplines and the mechanisms by which they interact.

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    Table of Contents:

    1. Overview: The developing Field of Osteoimmunology
    Yongwon Choi, Mark Horowitz, Hiroshi Takayanagi, Joseph Lorenzo
    2. The Origins of Bone Cells: Osteoclasts
    G. David Roodman, Deborah L. Galson
    3. Adaptive Immune Response
    David G. Hesslein, Hector L. Aguila, Mark C. Horowitz
    4. The Role of Bone Cells in Establishing the Hematopoietic Stem Cell Niche
    Henry Kronenberg, Joy Wu
    5. The Signaling Pathways Regulating
    Osteoblast Differentiation
    Jane Lian, Gary Stein
    6. The Signaling Pathways Regulating Osteoclast Differentiation
    Steven Teitelbaum, Roberta Faccio, Hiroshi Takayanagi, Yongwon Choi
    7. The Effects of Immune Cells Products (Cytokines and Growth Factors) on Bone Cells
    Joseph Lorenzo
    8. Interactions of Osteoblasts and Osteoclasts
    T. John Martin, Natalie A. Sims, Julian M. W. Quinn
    9. The Role of the Immune System in the Development of Osteoporosis
    Sundeep Khosla, B. Lawrence Riggs, Ulrike I. Moedder
    10. The Role of the Immune System in the Bone Loss of Inflammatory Arthritis
    Georg Schett, Steven Goldring
    11. The Role of the Immune System in the Bone Loss of Inflammatory Bowel Disease
    Francisco Sylvester, Anthony T. Vella
    12. The Role of the Immune System in Fracture Healing
    Louis Gerstenfeld, Thomas Einhorn, Brandon Steen
    13. The Role of the Immune System in the Development of Chronic Infections of Bone
    Brendan Boyce, Edward Schwarz, Lianping Xing
    14. The Role of the Immune System in Hematologic Malignancies, which Affect Bone
    Gregory Mundy, Claire M. Edwards, Jessica Fowler
    15. The Role of the Immune System in Dental Disease
    Dana Graves, Rayyan A. Kayal, Thomas Oates, Gustavo Garlet

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