Molecular Targets and Therapeutic Design
Series: Advances in Protein Chemistry and Structural Biology; 153;
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Product details:
- Publisher Elsevier Science
- Date of Publication 1 September 2026
- ISBN 9780443345234
- Binding Hardback
- No. of pages488 pages
- Size 229x152 mm
- Weight 450 g
- Language English 700
Categories
Long description:
Molecular Targets and Therapeutic Design, Volume 152 provides a comprehensive overview of the current landscape and future directions in the identification and exploitation of molecular targets for the development of new therapeutics. This volume brings together leading experts to discuss the fundamental principles of target discovery, validation, and the strategies used to design molecules that modulate biological pathways in disease. Topics covered in this new release include Recent Strategies and Approaches for the Development of Molecularly Targeted Nanomedicine, Transcriptomic Profiling for Therapeutic Target Discovery in Neuropsychiatric Conditions, Transcriptomic Insights into Hormone-Driven Malignancies: Toward Targeted Therapeutic Strategies, and much more.
Additional chapters cover Targeting Kinases in Neurodegenerative Diseases and Cancer: Structural Insights and Therapeutic Strategies, Small molecular therapeutic targets for neurodegenerative diseases, Signaling cascades of Tau protein, Understanding molecular role of lipids for Alzheimer's disease, Clinical Challenges and Therapeutic Strategies in Chordoma, Molecular Characterization and Experimental Models of Chordoma, Disordered Proteins as Fuzzy Viral Drug Targets, amongst other timely topics.
Table of Contents:
1. Recent Strategies and Approaches for the Development of Molecularly Targeted Nanomedicine
Balak Das Kurmi, Preeti Patel and Aman Kumar
2. Transcriptomic Profiling for Therapeutic Target Discovery in Neuropsychiatric Conditions
Karthick Vasudevan
3. Transcriptomic Insights into Hormone-Driven Malignancies: Toward Targeted Therapeutic Strategies
Karthick Vasudevan
4. Targeting Kinases in Neurodegenerative Diseases and Cancer: Structural Insights and Therapeutic Strategies
Anas Shamsi
5. Small molecular therapeutic targets for neurodegenerative diseases
Subashchandrabose Chinnathambi, Nagaraj Rangappa, Riddhi Bharatkumar Upadhyay, Sivasamy Ramasamy, Murugan Sevanan and Nathish Lakshman
6. Signaling cascades of Tau protein
Subashchandrabose Chinnathambi
7. Understanding molecular role of lipids for Alzheimer's disease
Subashchandrabose Chinnathambi
8. Neuroinflammation- molecular target based therapeutic approach
Deepraj Paul
9. Clinical Challenges and Therapeutic Strategies in Chordoma
Margot Martinez-Moreno and Beatrice Campilan
10. Molecular Characterization and Experimental Models of Chordoma
Margot Martinez-Moreno and Beatrice Campilan
11. Disordered Proteins as Fuzzy Viral Drug Targets
Selvaraj Chandrabose Sr.
12. Marine-Derived Bioactives as Precision Modulators of Molecular Targets: Emerging Paradigms in Therapeutic Design
Selvaraj Chandrabose Sr.
13. Precision Therapeutics for Wound Healing: Molecular Targets, Signaling Networks, and Advanced Drug Design Strategies
Ashokkumar Sibiya
14. Exploring the efficacy of ?-lactam and ?-lactamase inhibitors/?-lactam enhancer against carbapenem-resistant Acinetobacter baumannii: An in vitro and in silico analysis
George Priya Doss C
15. Screening of prospective biofilm-inhibitory drug candidates aimed at the biofilm-associated protein (BAP) in Staphylococcus aureus: An in-silico investigation
George Priya Doss C, Mangesh R, Sree Haryini and Mohanraj Gopikrishnan
