Molecular Diagnostics
Techniques and Applications for the Clinical Laboratory
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85 438 Ft
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Product details:
- Publisher Elsevier Science
- Date of Publication 23 December 2009
- ISBN 9780123694287
- Binding Hardback
- No. of pages744 pages
- Size 276x215 mm
- Weight 1640 g
- Language English 0
Categories
Long description:
Advances in genomic and proteomic profiling of disease have transformed the field of molecular diagnostics, thus leading the way for a major revolution in clinical practice. While the range of tests for disease detection and staging is rapidly expanding, many physicians lack the knowledge required to determine which tests to order and how to interpret results. Molecular Diagnostics provides a complete guide to the use and interpretation of molecular testing in the clinical arena. No other available resource offers this emphasis, comprehensive scope, and practical utility in the clinical setting.
MoreTable of Contents:
I. Introduction and Methodologyï¿1⁄2ï¿1⁄2
Quantivative PCR: an introduction
Signal Amplification Methods in Molecular Diagnostics
The Lab-on-a-Chip Approach for Molecular Diagnostics
Nucleic Extraction and Amplification
General Procedures
ï¿1⁄2ï¿1⁄2ï¿1⁄2ï¿1⁄2
II. Quality Assurance, Regulatory, and Ethical Issuesï¿1⁄2ï¿1⁄2
Billing and Reimbursement for Molecular Diagnostics
Molecular Pathology and Infectious Diseases
Ethical Considerations in Molecular Diagnostics
Quality Control, Assurance, Identification and Standards
ï¿1⁄2ï¿1⁄2
III. Genetic Diseaseï¿1⁄2ï¿1⁄2
Molecular Testing for Cystic Fibrosis and CFTR-Related Conditions
Carrier Testing for Neurogenetic Diseases
Hemochromatosis
Standards and Recommendations for Molecular Diagnostic Testing for Huntington Disease, the Autosomal Dominant Spinocerebellar Ataxias, and Friedreich Ataxia
ï¿1⁄2ï¿1⁄2
IV. Cancerï¿1⁄2ï¿1⁄2
The Role of Micro-RNAs in Cancer
Molecular Diagnostics in the Evaluation of Cancer: Modern Concepts and Overview
Gene Expression Analysis for Tumor Profiling GEA for TP
Molecular Diagnostics of Hematopoetic Malignancies
ï¿1⁄2ï¿1⁄2
V. Infectious Diseases ï¿1⁄2ï¿1⁄2
Viruses
Hepatic B and C Viruses
Molecular Diagnosis of Cytomegalovirus
Molecular Detection of Multiple Respiratory Viruses
Bacteria
Molecular Methods for Identification and Characterization of Acinetobacter species
Molecular Detection and Surveillance of Healthcare-Associated Infections
Molecular Detection Of Group B Streptococcus
Role of Molecular Techniques in the Epidemiologic Investigation Of Hospital-Acquired Infections
Human Papilloma Virus and its Role in Cervical Carcinoma
ï¿1⁄2ï¿1⁄2
VI. Specialized Applications of Molecular Testingï¿1⁄2ï¿1⁄2
Molecular HLA Typing Methods Used in Clinical Laboratories
Identification through DNA analysis in criminal and family relatedness investigations.
VII. Pharmacogeneticsï¿1⁄2ï¿1⁄2
Overview of Pharmacogenomics and Applications for the Modern Clinical Laboratory
UDP-Glucuronosyltransferase 1A1 and the Glucuronidation in Oncology Applications and Hyperbilirubinemia
Pharmacogenetics of P-450 Enzymes
Pharmacogenomics of Thiopurine Methyl Transferase (TPMT): Importance in Monitoring of Mercaptopurine/Azathioprine Therapy
