Molecular Biology of the Islets of Langerhans
- Publisher's listprice GBP 125.00
-
63 262 Ft (60 250 Ft + 5% VAT)
The price is estimated because at the time of ordering we do not know what conversion rates will apply to HUF / product currency when the book arrives. In case HUF is weaker, the price increases slightly, in case HUF is stronger, the price goes lower slightly.
- Discount 20% (cc. 12 652 Ft off)
- Discounted price 50 610 Ft (48 200 Ft + 5% VAT)
Subcribe now and take benefit of a favourable price.
Subscribe
63 262 Ft
Availability
Estimated delivery time: In stock at the publisher, but not at Prospero's office. Delivery time approx. 3-5 weeks.
Not in stock at Prospero.
Why don't you give exact delivery time?
Delivery time is estimated on our previous experiences. We give estimations only, because we order from outside Hungary, and the delivery time mainly depends on how quickly the publisher supplies the book. Faster or slower deliveries both happen, but we do our best to supply as quickly as possible.
Product details:
- Publisher Cambridge University Press
- Date of Publication 22 February 1990
- ISBN 9780521362047
- Binding Hardback
- No. of pages364 pages
- Size 235x156x27 mm
- Weight 673 g
- Language English 0
Categories
Short description:
The islets of Langerhans, the primary source of hormone production in the pancreas, have been the focus of research into the nature of diabetes for decades.
MoreLong description:
The islets of Langerhans, the primary source of hormone production in the pancreas, have been the focus of research into the nature of diabetes for decades. In recent years, the molecular biology of this multiendocrine organ has been intensively investigated, with a corresponding increase in our understanding of the normal and pathological functioning of islet cells. Molecular Biology of the Islets of Langerhans provides a comprehensive treatment of molecular studies on the synthesis of insulin, glucagon, somatostatin and pancreatic polypeptide. In addition, this volume presents contemporary hypotheses and explanations, at the molecular level, of the defects in islet cells that may lead to diabetes. The material presented here will be essential reading for researchers in human endocrinology and, in particular, for those working in the area of diabetes research.
"Indisputably this book will provoke a real interest among the endocrinologists, biochemists, molecular biologists and all investigators working in the area of diabetes research." R. Wegmann, Cellular and Molecular Biology
Table of Contents:
Preface Hiroshi Okamoto; Introductory overview Hiroshi Okamoto; Part I. The Molecular Biology of Peptide Hormones in the Islets of Langerhans: 1. The organization and structure of insulin genes Graeme I. Bell and Susumu Seino; 2. The regulation of insulin gene expression Michael D. Walker; 3. The translational control of proinsulin synthesis by glucose Nobuyuki Itoh; 4. The structure and regulation of the glucagon gene Joel F. Habener; 5. The structure and regulation of the somatostatin gene Joel F. Habener; 6. The mosaic evolution of the pancreatic polypeptide gene Hiroshi Yamamoto, Hideto Yonekura and Koji Nata; 7. The structure and expression of genes of vasoactive intestinal peptide and related peptides Takashi Yamagami; 8. Pancreastatin: a novel pancreatic hormone Kazuhiko Tatemoto; 9. The processing of peptide precursors Thue W. Schwartz; Part II. Molecular Aspects of Diabetes Mellitus: 10. The molecular basis of experimental diabetes Hiroshi Okamoto; 11. Class II histocompatibility genes and diabetes David Owerbach; 12. The role of the insulin gene in diabetes: use of restriction fragment length polymorphisms in diagnosis Steven C. Elben and M. Alan Permutt; 13. Abnormal products of the human insulin gene Howard S. Tager; 14. A novel gene, rig, activated in insulinomas Shin Takasawa, Chiyoko Inoue, Kiyoto Shiga and Motoo Kitagawa; 16. Defects of signal transduction in a tumoral islet cell line Willy J. Malaisse; Index.
More
