Molecular Biology of Cancer
Mechanisms, Targets, and Therapeutics
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Product details:
- Edition number 6
- Publisher OUP Oxford
- Date of Publication 14 January 2026
- ISBN 9780198899693
- Binding Paperback
- No. of pages520 pages
- Size 245x187x21 mm
- Weight 989 g
- Language English 671
Categories
Short description:
Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers an accessible, engaging, and optimistic account of cancer biology for undergraduate and graduate students.
MoreLong description:
The most engaging and accessible account of cancer biology which clearly links our understanding of cancer with the development of new therapeutics.
Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers an accessible, engaging, and optimistic account of cancer biology for undergraduate and graduate students.
Key features
- Describes the theoretical basis of cancer biology and shows how this theory is applied to develop new cancer therapies, giving students a clear appreciation of how theoretical knowledge can be translated into therapeutic strategies
- Draws on the latest research in cancer biology
- Features a variety of learning features to help students engage with the concepts presented: 'Pause and think'; 'How do we know that?'; 'In the clinic'; self-tests; and activities
New to this edition
- New themes that weave throughout the book, such as the two-way interactions between the microenvironment and the tumour, systemic effects of cancer, and the role of plasticity and heterogeneity in cancer evolution
- Expanded coverage of cancer genomics, including single cell genomics and spatial transcriptomics, highlighted in the concluding chapter
- A new feature called 'In the clinic' that highlights current or potential applications of cancer biology to clinical practice
- Updates on newly approved cancer therapeutics
- Includes additional primary data from the literature and key references to provide a resource of up-to-date experimental evidence
- Expanded artwork programme and new 'figure sequences' (in the enhanced e-book) to help readers understand molecular pathways over time
Digital formats and resources
The 6th edition is available for students and institutions to purchase in a variety of formats: the e-book and Science Trove offer a mobile experience and convenient access along with multiple choice questions, audio clips, functionality tools, navigation features and links that offer extra learning support.
For more information about e-books, please visit https://www.oxfordtextbooks.co.uk/ebooks
A comprehensive resource outlining the principles of cancer biology, with a clear structure and good use of diagrams and learning features.
Table of Contents:
Introduction
The transformable cancer genome: mutations versus repair
Regulation of gene expression
Growth factor signaling and oncogenes
The cell cycle
Tumour suppressor genes
Apoptosis
Cancer stem cells, lineage plasticity and disrupted differentiation: focus on colon cancer and leukemias
Metastasis
Angiogenesis
Reprogrammed metabolism and diet
Tumour immunology and immunotherapy
Inflammation, infection, and the microbiome
Cancer genomics and other methods for research and clinical development
