Mechanobiology
From Molecular Sensing to Disease
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32 744 Ft
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Product details:
- Publisher Elsevier Science
- Date of Publication 4 December 2019
- ISBN 9780128179314
- Binding Paperback
- No. of pages254 pages
- Size 234x190 mm
- Weight 520 g
- Language English 0
Categories
Long description:
Mechanobiology: From Molecular Sensing to Disease will provide a review of the current state of understanding of mechanobiology and its role in health and disease. It covers:ï¿1⁄2Current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli,ï¿1⁄2A review of diseases that with known or purported mechanobiological underpinnings;ï¿1⁄2The role of mechanobiology in tissue engineering and regenerative medicine; Experimental methods to capture mechanobiological phenomena;ï¿1⁄2Computational models in mechanobiology.
Table of Contents:
Section 1: Mechanobiological basis of diseases1.1 Osteoporosis1.2 Cardiovascular mechanics and disease1.3 Glaucoma and eye diseases1.4 Growth and development1.5 Tissue engineering and regenerative medicine
Section 2: Cellular basis of Mechanobiology 2.1 Cells as strain gages and load cells2.2 Cell - extracellular matrix interactions2.3 Mechanobiological pathways2.4 Mechanically mediated epigenetics
Section 3: Experimental methods3.1 Effects of shear stress on cells3.2 Three-dimensional culture systems3.3 Bioreactors3.4 Tissue and organ on a chip systems
Section 4: Computational simulations in mechanobiology4.1 Cell aggregation4.2 Growth models5. Future prospects and challenges6. Bibliography7. Glossary
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