Mechanisms of Cortical Development
Series: Monographs of the Physiological Society; 48;
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Product details:
- Publisher OUP Oxford
- Date of Publication 20 April 2000
- ISBN 9780192624277
- Binding Hardback
- No. of pages328 pages
- Size 242x160x23 mm
- Weight 674 g
- Language English
- Illustrations line figures 0
Categories
Short description:
This is the first book which attempts to bring together what is known about the fundamental mechanisms that underlie the development of the cortex in mammals. In contrast to other texts of developmental biology, Mechanisms of Cortical Development integrates cellular development and structural morphology with events at the biochemical and genetic level. In addition, the authors derive several theoretical models for the action of different cell types.
MoreLong description:
This is the first book that attempts to bring together what is known about the fundamental mechanisms that underlie the development of the cortex in mammals. Ranging from the emergence of the forebrain from the neural plate to the functioning adult form, the authors draw on evidence from several species to provide a detailed description of processes at each stage. Where appropriate, evidence is extrapolated from non-mammalian species to generate hypotheses about mammalian development. In contrast to other texts of developmental biology, Mechanisms of Cortical Development integrates information on regulatory processes at the levels of molecules, cells and metworks. The authors draw together an extensive literature on cellular development and structural morphology, biochemical and genetic events and hypotheses that have been subject to mathematical modelling. Important metholdogies, such as transgenics and formal modelling, are explained for the non-specialist. Major future challenges are clearly identified. This is a unique contribution to the literature, combining the fundamentals of experimental developmental neurobiology with accessible neural modelling. It will be essential reading for neuroscientists in general as well as those with a particular interest in development.
... we recommend this book for all who want not just to list the various mechanisms at work in cortical development, but to fit them into the overall picture
Table of Contents:
Chapter 1 - Introduction
Chapter 2 - Early development of the telencephalon
Chapter 3 - Molecular recognition of early forebrain and cortical development
Chapter 4 - Guidance of axons and innervation of cortical structures
Chapter 5 - Map formation
Chapter 6 - Mechanisms controlling the development of cortical connections at the target
Chapter 7 - Functional development of the cortex
Glossary
