Managing Health in the Genomic Era
A Guide to Family Health History and Disease Risk
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Product details:
- Publisher Elsevier Science
- Date of Publication 29 June 2020
- ISBN 9780128160152
- Binding Paperback
- No. of pages238 pages
- Size 228x152 mm
- Weight 390 g
- Language English 24
Categories
Long description:
In Managing Health in the Genomic Era: A Guide to Family Health History and Disease Risk, Drs. Vincent C. Henrich, Lori A. Orlando, and Brian H. Shirts discuss the practical considerations surrounding the use of genomic and genetic tests to manage patient health, to provide adult disease risk assessment, to improve diagnosis, and to support effective interventions and treatment. In 10 chapters, evidence-based information and case studies are described and examine the central place of family health history (FHH) in genomic medicine, tools and strategies for compiling and analyzing family health history, how to identify existing and novel genetic markers, how to identify lineage specific (or rare) variants within families, and how to find effective interventions based on genetic testing results and FHH. Factors that influence clinical practice, including gene-environment interactions, FHH social networking, direct to consumer (DTC) genetic testing and data sharing, algorithms for analyzing genetic data, and patient counseling are discussed from the standpoint of clinical practice.
Here, frontline healthcare providers will discover succinct commentary and key examples to assist with their local needs. Relevant principles of genetic biology and inheritance are explored and guidance on available support networks and online resources is also provided.
MoreTable of Contents:
1. The growing medical relevance and value of family health history2. Family health history's place in genomic medicine3. The connection between genetic variation,family health history, and disease risk4. Family-specific genetic variants: Principles, detection, and clinical interpretation5. Genes and cancer: Implications for FHH analysis6. Using family health history to identify and reduce modifiable disease risks7. Technology for family health history and collection and analysis8. Family health history and genetic counseling9. Current and future trends in diagnostics and treatment10. Current and future trends to integrate family health history with clinical programs to improve population health
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