Introduction to Modeling in Physiology and Medicine
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Product details:
- Edition number 2
- Publisher Elsevier Science
- Date of Publication 2 August 2019
- ISBN 9780128157565
- Binding Paperback
- No. of pages384 pages
- Size 234x190 mm
- Weight 770 g
- Language English 0
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Long description:
Introduction to Modeling in Physiology and Medicine, Second Edition, develops a clear understanding of the fundamental principles of good modeling methodology. Sections show how to create valid mathematical models that are fit for a range of purposes. These models are supported by detailed explanation, extensive case studies, examples and applications. This updated edition includes clearer guidance on the mathematical prerequisites needed to achieve the maximum benefit from the material, a greater detail regarding basic approaches to modeling, and discussions on non-linear and stochastic modeling. The range of case study material has been substantially extended, with examples drawn from recent research experience.
Key examples include a cellular model of insulin secretion and its extension to the whole-body level, a model of insulin action during a meal/oral glucose tolerance test, a large-scale simulation model of type 1 diabetes and its use in in silico clinical trials and drug trials.
MoreTable of Contents:
1. Introduction2. Physiological Complexity and the Need for Models3. Models and the Modeling Process4. Modeling the Data5. Modeling the System6. Model Identification7. Parametric Models - The Identifiability Problem8. Parametric Models - The Estimation Problem9. Non-parametric Models - Signal Estimation10. Model Validation11. Case Studies
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