Immunology
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Product details:
- Publisher OUP India
- Date of Publication 10 March 2011
- ISBN 9780198068266
- Binding Paperback
- No. of pages464 pages
- Size 244x182x20 mm
- Weight 636 g
- Language English 0
Categories
Short description:
Immunology is the study of the nature of the functioning of the immune system and how it protects the body in a hostile environment where many infectious organisms lurk.
MoreLong description:
The early chapters of the book provide a broad overview of the immune system and its functioning. The subsequent chapters present the importance of discriminating self from non-self through pattern recognition receptors (PRRs), structure and function of antibodies, major histocompatability complex, antigen receptors of the adaptive immune system, cellular interactions that lead to activation of T and B lymphocytes, immune responses against various categories of
pathogens, and manipulation of the immune system by vaccination and various vaccine strategies. The book also includes clinically significant areas and hypersensitivity states including allergy, immunodeficiency disorders, transplantation and tumor immunology. There is also a special emphasis om the
HIV/AIDS pandemic against which efforts are on at a massive scale. Tolerance and autoimmunity have also been linked for a better understanding of the mechanisms that could lead to autoimmune diseases.
An additional feature of the book is the inclusion of various techniques, immunoassays, and experimental systems provided in the appendix. ELISA and other immunological techniques like agglutination and precipitation having wide ranging applications have also been included in the book.
Table of Contents:
The immune system - an introduction
Innate immune response to infections
The lymphoid system and cells of adaptive immunity
Antigens and antibodies
Major histocompatability complex (MHC)
Generation of antibody diversity and B lymphocyte development
Cytokines
T lymphocyte maturation and activation
Effector mechanisms of cell-mediated immunity
Activation of B lymphocytes
Effector mechanisms of humoral immunity
Immune response against microbes
Vaccination and vaccine strategies
Hypersensitivity reactions
Immunologic tolerance and autoimmunity
Immunodeficiency diseases
Transplantation and graft rejection
Tumor immunology
Appendix A Immunological techniques: principles and application
Appendix B Cumulative glossary
