Human Baroreflexes in Health and Disease
Series: Monographs of the Physiological Society; 43;
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Product details:
- Publisher Clarendon Press
- Date of Publication 12 March 1992
- ISBN 9780198576938
- Binding Hardback
- No. of pages588 pages
- Size 241x160x38 mm
- Weight 1088 g
- Language English
- Illustrations halftones, line illustrations 70
Categories
Short description:
The function of the cardiovascular system has to be monitored and adjusted constantly to respond to the abrupt changes in arterial blood pressure that occur in everyday life, as a consequence of exercise, for example. The baroreflexes are one of the most important of the control mechanisms involved. This is the first book devoted to human baroreflexes, and it places the most recent understanding of human physiology solidly in the context of knowledge derived from animals. It deals comprehensively with baroreflex involvement in human diseases, including high blood pressure, heart failure, and sudden cardiac death.
MoreLong description:
BL The first book devoted to human baroreflexes
A comprehensive review of baroreflex involvement in human diseases, this book places the most recent understanding of human physiology solidly in the context of knowledge from animals. This book secures a place for human studies in the understanding of baroreflex physiology and pathophysiology and celebrates the advances made. By describing clearly the existing deficiencies in the understanding of baroreflex mechanisms, it points a way for future research in this exciting and important area of medical science. Nerve endings in the walls of the carotid sinuses and the aortic arch transduce arterial pressure changes and provide the central nervous system with a steady stream of encoded information. On the basis of this information, efferent autonomic neural activity is modulated finely, and the neurohumoral milieu of the heart and blood vessels is adjusted on a second-to-second basis. The arterial baroreflex may be the most important of the cardiovascular control mechanisms, because the baroreflex, above all other reflex mechanisms is the one whose speed is most adequate to respond rapidly to the abrupt transients of arterial pressure that occur in daily life.
This book will help to fix a place for human studies in the understanding of baroreflex physiology and pathophysiology. It is intended as a celebration of the advances that have been made and, by describing clearly the existing deficiencies in the understanding of baroreflex mechanisms, it points a way for future research in this exciting and important area of medical science.
Table of Contents:
Part A: General considerations: Introduction; History; Baroreflex anatomy; Part B: Methods for Human Research: Valvalva's manoeuvre; Selective methods; Part C: Physiology: Afferent baroreceptor activity; Reflex interactions; Efferent baroreflex responses; Effector responses to baroreceptor forcings; Part D: Pathophysiology: Baroreflex malfunction in cardiovascular patients: general principles; Hypertension; Myocardial ischaemia; Dysrhythmias; Congestive heart failure; Carotid sinus reflex hypersensitivity.
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