| ISBN13: | 9783030324582 |
| ISBN10: | 3030324583 |
| Binding: | Hardback |
| No. of pages: | 364 pages |
| Size: | 235x155 mm |
| Weight: | 919 g |
| Language: | English |
| Illustrations: | 8 Illustrations, black & white; 12 Illustrations, color |
| 0 |
HIV/AIDS: Immunochemistry, Reductionism and Vaccine Design
EUR 53.49
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Marc Van Regenmortel was a Professor of Virology at various Universities in South Africa (Stellenbosch and Cape Town) and France (Strasbourg), and was head of the Immunochemistry Laboratory at the CNRS Molecular Biology Institute in Strasbourg for 22 years. He served as President of the International Committee on Taxonomy of Viruses and published a dozen books and 420 papers and reviews on the immunochemistry of peptides and viruses, viral taxonomy and biosensor technology. He was an advisor to the South African AIDS Vaccine Initiative and is currently an associate editor of Journal of Molecular Recognition, Archives of Virology, Advances in Virus Research, Journal of Immunological Methods, Analytical Biochemistry and Frontiers in Immunology.
He is an Adjunct Professor of the Medical University of Vienna.
This book gathers a series of pivotal papers on the development of an HIV/AIDS vaccine published in the last two decades. Accompanied by extensive comments putting the material into an up-to-date context, all three parts of the book offer a broad overview of the numerous unsuccessful attempts made in recent years to develop a preventive HIV vaccine. Providing a detailed review and analysis of studies published from 1998 to the present day, it examines the likely reasons for the failure to develop an HIV vaccine despite multi-million dollar investments.
Part I Immunochemistry
1 What is a B cell epitope
2 Molecular design versus empirical discovery in peptide
-based vaccines. Coming to terms with fuzzy recognition sites and ill
-defined structure?function relationships in immunology
3 Synthetic Peptide Vaccines and the Search for Neutralization B Cell Epitopes
