- Publisher's listprice GBP 83.00
-
42 006 Ft (40 006 Ft + 5% VAT)
The price is estimated because at the time of ordering we do not know what conversion rates will apply to HUF / product currency when the book arrives. In case HUF is weaker, the price increases slightly, in case HUF is stronger, the price goes lower slightly.
- Discount 20% (cc. 8 401 Ft off)
- Discounted price 33 605 Ft (32 005 Ft + 5% VAT)
Subcribe now and take benefit of a favourable price.
Subscribe
42 006 Ft
Availability
Estimated delivery time: In stock at the publisher, but not at Prospero's office. Delivery time approx. 3-5 weeks.
Not in stock at Prospero.
Why don't you give exact delivery time?
Delivery time is estimated on our previous experiences. We give estimations only, because we order from outside Hungary, and the delivery time mainly depends on how quickly the publisher supplies the book. Faster or slower deliveries both happen, but we do our best to supply as quickly as possible.
Product details:
- Publisher Cambridge University Press
- Date of Publication 28 March 2002
- ISBN 9780521799591
- Binding Paperback
- No. of pages270 pages
- Size 248x174x16 mm
- Weight 582 g
- Language English
- Illustrations 9 b/w illus. 13 tables 0
Categories
Short description:
An integrated, multidisciplinary account of the virus, its biology and clinical manifestations.
MoreLong description:
Hepatitis C infects 170 million people worldwide, and has been labelled the 'silent epidemic' as a result of its concealed attack on the liver. This multidisciplinary overview covers basic concepts related to the discovery of the virus, development of serological and nucleic acid tests to detect infection, the structure of the virus genome, generation of virus gene products, and proposed replication scheme. It then goes on to introduce the epidemiology, transmission, pathogenesis of infection, the development of hepatocellular carcinoma associated with chronic virus infection, and current strategies for treatment. The book then discusses advances in cell culture systems, animal models of infection, and emerging treatments and vaccine development. Through its coverage of basic science, clinical consequences, and methods of research, this integrated and accessible account will be of immense value to biomedical scientists and clinicians alike, and a useful introduction for all those studying the virus and its effects.
'The diligent reader of this book will come away with a thorough grounding in the virology and immunopathology of hepatitis C, know what the major sources of further information are, and understand why this infection is at once enigmatic, insidiously progressive, difficult to treat and hard to immunize against. Thoroughly recommended! Epidemiology and Infection
Table of Contents:
Preface; Part I. Basic Principles: 1. Background; 2. The virus; 3. Epidemiology and transmission; 4. Natural history of infection; 5. Pathogenesis of infection; 6. HCV and hepatocellular carcinoma; 7. Extrahepatic sites for hepatatis C; 8. HCV and autoimmune diseases; 9. Clinical aspects of the disease; 10. Current therapeutic approaches; 11. NS5A and interferon resistance; Part II. Recent Advances: 12. Propagation of virus in culture; 13. Understanding the natural history of HCV; 14. HCV animal models; 15. Vaccine research; Part III. Experimental Approaches: 16. New systems to understand HCV biology; 17. New antiviral screening assays; 18. Antiviral gene therapy; Part IV. Protocols and Techniques: 19. Sample collection, preparation and storage; 20. HCV RNA in blood and tissue samples; 21. HCV RNA genotypes and quasispecies; 22. Replication of HCV in tissue culture; 23. NS3 protease, helicase and NTPase; 24. Characterization of NS5B; Part V. Outstanding Questions and Emerging Areas for Investigation; References; Index.
More
