Hemoglobin
Insights into protein structure, function, and evolution
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48 536 Ft
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Estimated delivery time: In stock at the publisher, but not at Prospero's office. Delivery time approx. 3-5 weeks.
Not in stock at Prospero.
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Delivery time is estimated on our previous experiences. We give estimations only, because we order from outside Hungary, and the delivery time mainly depends on how quickly the publisher supplies the book. Faster or slower deliveries both happen, but we do our best to supply as quickly as possible.
Product details:
- Publisher OUP Oxford
- Date of Publication 4 December 2018
- ISBN 9780198810681
- Binding Hardback
- No. of pages256 pages
- Size 249x196x17 mm
- Weight 750 g
- Language English
- Illustrations Over 140 illustrations 0
Categories
Short description:
Provides a synthesis of our current understanding of hemoglobin (Hb) function and evolution, and illustrates how research on this protein has provided more general insights into mechanisms of protein evolution and biochemical adaptation.
MoreLong description:
The primary aim of this book is to provide a synthesis of our current understanding of hemoglobin function and evolution, and to illustrate how research on one particular family of proteins has provided general insights into mechanisms of protein evolution and biochemical adaptation. In doing so, it will also promote an appreciation of how mechanistic insights into protein function can enrich our understanding of how evolution works. Reciprocally, it highlights how approaches in evolutionary genetics (such as phylogenetic comparative methods and ancestral sequence reconstruction) can be brought to bear on questions about the functional evolution of proteins. This treatise on the functional evolution of hemoglobin illustrates how research on a single, well-chosen model system can enhance our investigative acuity and bring key conceptual questions into especially sharp focus.
MoreTable of Contents:
Principles of protein structure
A study in scarlet: The role of hemoglobin in blood gas transport
Allosteric theory
Hemoglobin structure and allosteric mechanism
Evolution of the vertebrate globin gene family
Gene duplication and hemoglobin isoform differentiation
The evolution of novel hemoglobin functions and physiological innovation
Mechanisms of biochemical adaptation to environmental hypoxia
Darwin's molecule: Evolutionary insights into mechanisms of biochemical adaptation and protein evolution
