Genomics and Clinical Medicine
Series: Oxford Monographs on Medical Genetics; No. 53;
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Product details:
- Publisher OUP USA
- Date of Publication 17 April 2008
- ISBN 9780195188134
- Binding Hardback
- No. of pages672 pages
- Size 226x282x40 mm
- Weight 2467 g
- Language English
- Illustrations numerous figures and tables 0
Categories
Short description:
An important milestone in medicine has been the recent completion of the Human Genome Project. The identification of 30,000 genes and their regulatory proteins provides the framework for understanding the metabolic basis of disease. This advance has also laid the foundation for a broad range of genomic tools that have opened the way for targeted genetic testing in a number of medical disorders. This book is designed to be the first major text to discuss genomics-based advances in disease susceptibility, diagnosis, prognostication, and prediction of treatment outcomes in various areas of medicine. After building a strong underpinning in the basic concepts of genomics, the authors of this book, all leaders in the field, proceed to discuss a wide range of clinical areas and the applications now afforded by genomic analysis.
MoreLong description:
An important milestone in medicine has been the recent completion of the Human Genome Project. The identification of 30,000 genes and their regulatory proteins provides the framework for understanding the metabolic basis of disease. This advance has also laid the foundation for a broad range of genomic tools that have opened the way for targeted genetic testing in a number of medical disorders. This book is designed to be the first major text to discuss genomics-based advances in disease susceptibility, diagnosis, prognostication, and prediction of treatment outcomes in various areas of medicine. After building a strong underpinning in the basic concepts of genomics, the authors of this book, all leaders in the field, proceed to discuss a wide range of clinical areas and the applications now afforded by genomic analysis.
I can see it having a place in the libraries of hospitals and clinical departments alongside other classic textbooks.
Table of Contents:
SECTION 1: GENERAL GENOMICS
From Genes to Genome - a Historical Perspective
The Human Genome - Structure and Organization
Human Functional Genomics and Proteomics
Epigenomics and Human Disease
Genomic Perspectives of Human Development
Genetic and Genomic Approaches to Taxonomy of Human Diseases
Genomic Technologies
Nutritional Genomics
Pharmacogenomics: Drug Development, Drug Response and Precision Medicines
SECTION 2: CLINICAL GENOMICS
Clinical Medicine in the Genome Era - An Introduction
Complex Cardiovascular Disorders
Diabetes Mellitus and Obesity
Chronic Renal Disease
Haemostasis and Thrombosis
Disorders of Platelets
Applications in Critical Care Medicine
Seizure Disorders
Neurodegenerative Disorders: Tauopathies and Synucleinopathies
Neuropsychiaric Diseases I: Schizophrenia
Neuropsychiaric Diseases II: Mood Disorders
Asthma and Chronic Obstructive Pulmonary Disease
Inflammatory Bowel Disease
Cancer Genomics: Mechanisms, Diagnosis and Therapeutic Implications
Hematological Malignancies: The Paradigm of Acute Myeloid Leukemia
Infectious Diseases: Susceptibility, Resistance, Response, and Anti-Microbial Therapy
Chronic Inflammatory Disorders
Immunological Disorders
Applications in Clinical Pediatrics
Learning and Behavioural Disorders
Complex Ophthalmic Disorders
Applications in Audiological Medicine
Complex Skin Diseases I: Psoriasis
Complex Skin Diseases II: Atopic Dermatitis
Complex Skin Diseases III: Diseases of the Epidermis and Appendages, Skin Pigmentation and Skin Cancer
Osteoporosis and Related Disorders
Applications in Obstetrics & Gynaecology and Reproductive Medicine
Stem Cell Genomics, Cell-based Therapy and Regenerative Medicine
SECTION 3: HEALTH GENOMICS
Genomics and Global Health
Genetic Testing and Genomic Screening
Ethical Issues in Human Genomics
The Regulation of Human Genomics Research
